rno-mir-296: Rno-mir-296 is a microRNA that has been studied in various contexts. In a study comparing qPCR and deep-sequencing results, it was found that the expression patterns of most miRNAs were consistent, except for four miRNAs including rno-mir-296, which showed minor discrepancies [PMC3441217]. Rno-mir-296 was found to be down-regulated and predicted to target E2f1, which was significantly up-regulated after treatment with furan [PMC2974699]. In another study, rno-mir-296 was one of the four miRNAs that were significantly upregulated in stress-induced models [PMC3961114]. Additionally, rno-mir-296 showed the greatest change in expression with an approximately 8-fold down-regulation [PMC2974699]. The study also identified other differentially expressed miRNAs in stress-induced models, including rno-miR-141, rno-miR-382, and rno-miR-219-5p (upregulated) and miR-135a and miR-466b (downregulated) [PMC3961114]. These findings suggest that rno-mir-296 may be involved in stress-induced myocardial injury at the molecular level. Overall, rno-mir-296 has been shown to exhibit altered expression patterns in different contexts and may play a role in various biological processes.
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