hsa-mir-520e: Hsa-mir-520e is a microRNA that has been identified as the target miRNA of SYDE1 and has shown favorable outcomes in gliomas [PMC8552071]. To assess the prognostic ability of hsa-mir-520e and its target lncRNAs (FGD5-AS1, MIR17HG, and SNHG16), their expression levels were measured [PMC8552071]. AKTIP is targeted by hsa-miR-520b and hsa-mir-520e, CDK6 is targeted by hsa-miR-320a and hsa-miR-449a, PAG1 is targeted by hsa-miR-429 and hsa-miR-1193, and RORA is targeted by hsa-miR-107 and hsa-miR-137 [PMC6595612]. In COLO 320 and COLO 205 cells, miRNAs such as hsa-mir-21, hsa-mir-20a, hsa-mir-92a-1, among others were upregulated and involved in cell cycle regulation, cell differentiation, migration, and invasion. Conversely, miRNAs such as has mir 539 were downregulated in both primary and metastatic colon cancer cells [PMC9941246]. The biological targets of differentially expressed miRNAs (DEMs) were predicted using four different software programs. However, the gene targets of specific miRNAs like has mir 455 were not predicted using the PicTar software [PMC7410007].