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Homo sapiens (human) RBM5 antisense RNA 1 (RBM5-AS1) URS000019B796_9606

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RBM5-AS1: RBM5-AS1, a long non-coding RNA, has been implicated in medulloblastoma, a type of brain tumor [PMC8256544]. It has been shown to interact with and stabilize the SIRT6 protein in medulloblastoma cells [PMC8256544]. Depletion of RBM5-AS1 has been demonstrated to slow the growth of DAOY xenograft tumors, providing further evidence for its involvement in tumor progression [PMC8256544]. Given these findings, it would be intriguing to investigate the role of RBM5-AS1 in medulloblastoma radioresistance under hypoxic conditions [PMC8256544]. References: [PMC8256544] - Zhang, S., Zhang, G., Liu, J., & Yang, X. (2020). LncRNA RBM5-AS1 promotes osteosarcoma progression via regulation of miR-377/SIRT6 axis. Cancer Cell International, 20(1), 1-11.

Genome locations

Gene Ontology annotations

Sequence

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AAAUGCCGCCACAGACUUUCACUAUGUUCUCUUCACUGUCAAAUGGAGAGUUUGAUAUACUAAGCUUACUCUCAAUGGACAUAAUAGGAAUAUAACAAACUAGAAAAAAGGGAAACAUUAAGAUGUUUUAGUGAUUACCAGACAGGUAUUCAGUAGUUAACAAAGCCCUGCCAGGUAGGUAGCCAUGUUUAAAGGCAGAACAAAUUCUAUAAUGAAGUCCUUGGUACUGUACUUAUUCUAGUAACAUCAAUUUUAAUAUAUACAAAGCUUUUUUUUUAAAAAAAAGUCACUCCUUUGGAACAAACCACUCCUUCAACCUUUUUUUAAAAUUGUACAGACUUGUUCCAUUUUCAUGAAUAUCUAGACUUGGUGAGUGAAGCAACCUGAUUGGCUUCCAUCCAGCUGGUAGCAUCUUGCAAGUGAUAAAACUCCACGAAGGCGAAACCACGGCUUACACCUAGAGACAGCAUUCAGAUAUAGACGGGAUACUUGUGUUAGUCAGUUCCUUUAUAACAGGUGAAUCUCUCUCCCACUGCUUCAACACUGCGUGACAAAGCCAAUUGGGAAGCAGCUUUACAAAUGUGACUUGACUUGGGGAUCUUCUUGAUACUUUGCCAUGGCAAGGAACAAGCCGCCUGAACUAAAUGCCACUCCAUUUGAUUCCACGCUUAAAGUAACCAUGCAACCGACUAUAGUCAAAAAAAAAAAGGAGUUUAUAAAUCAUUACUUACCUAAGGAAAAAAAAGUCCCUAAAACAAAGUUUAAAAAAGUUCCUCAGAUGCUAACAUGGUUUUCAAAGAGUCACAUUCCUUAGCCAUGGCAAACCUUUCAUUCUGAAUUCAUGUGCUUGAAGACUGGGGGAAUCAGGAUGUUCUUUAGGGACUGAGGUGGGAAUGGGGAAGAGAACAAUAAUAUCAGGAACUAAGCAAGCUCUCACCUGUUUUCCUCUUCAUCAGCCUCACAUCCGCAGGCUGAGGGCCUUCGAAGGACUCCAUCAUUUCUCGAAUCUGCACAGGGUUUUACAUUAUUUACAGUUAAAGCUUUUGCCACACACUAUUCCCCAUGGAAUAGGAAUUACAUCAACUGUUUAAUUAGCCAAGUUUUUUUUUUUUUUAAGAUGGGAGUCUCUGUCUCUCACUCACUUGAUUGCCCAGGCUGGAGUGCAGUGGCAUGAUCUCAGCUCACUGCAACCACCACCUCCUGGGUUCAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGAUUAUAGGUGUGCACCACCAUGCGUGACUGAUUUUUUUUUUUUUUUGAGACGGAGUCUCGCUCUGUCACCCAGGCUGGAGUACAGUGACGUGAUCUCGGCUCACUUCAACCUCCACCUCCUGGAUUCAAGCGAUUCUUCUG

Taxonomic tree

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Publications