bta-miR-7: Bta-mir-7 is a microRNA that has been studied in various contexts. It has been shown to exhibit a trend in regulation in some studies [PMC5736867]. In addition, bta-mir-7 has been found to be differentially expressed between fresh and frozen sperm [PMC7214931]. It is also associated with important signaling pathways such as insulin and muscle development, as well as feed efficiency [PMC6244318]. Bta-mir-7 has been previously associated with adipose tissue and feed efficiency in bovine studies [PMC6244318]. Furthermore, bta-mir-7 is among the most abundant miRNAs found in development stages of cattle [PMC7073773]. In cattle-yak, the expression of bta-mir-7 is down-regulated, suggesting its involvement in reproductive processes and male sterility [PMC9581192]. The target genes of bta-mir-7 include MYRFL, FANCA, INSL3, USP9X, and SHF [PMC9581192]. The expression levels of bta-miR-449a and its target genes FANCA, MYRFL, and SHF have also been validated using qPCR [PMC9581192]. Bta-mir-7 has also been used as a positive control for normalization purposes in some studies [PMC6785219]. Overall, bta-mir-7 is involved in various signaling pathways and plays important roles in reproductive processes and male sterility. It is also used as a reference for normalization purposes.
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