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Bos taurus (cattle) bta-miR-487b URS000015B295_9913

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bta-mir-487b: bta-mir-487b is a microRNA that has been found to be correlated with methane metabolism and several other pathways in the rumen [PMC9378797]. It has the highest number of correlations with different genera and is associated with sugar metabolism, transcription factors, and transporters [PMC9378797]. However, its relationship with bacteria is not well understood yet [PMC9378797]. Interestingly, bta-mir-487b is negatively correlated with Gram-positive strains despite being positively correlated with the peptidoglycan biosynthesis pathway [PMC9378797]. It also shows a strong correlation with a high number of taxa [PMC9378797]. In terms of expression levels, bta-mir-487b is differentially expressed in peak and late lactation in bovine tissue, being higher in late lactation compared to peak lactation [PMC3498112]. Additionally, bta-mir-487b is highly expressed in the fetal stage and other differentiated tissues but not found in bovine calf or adult muscles [PMC3563516]. References: [PMC9378797] - Morgavi DP et al. (2021) Rumen microbiome-host interactions: Insights into the role of microRNAs. Front Microbiol. 12: 637637. doi: 10.3389/fmicb.2021.637637. [PMC3498112] - Li R et al. (2012) Comparative microRNAome analysis of the mammary gland tissues from two breeds of cattle after removal of suckling stress using deep sequencing. PLoS One 7(9): e44587. [PMC3563516] - Li R et al. (2013) Comparative analysis of muscle miRNAs between prenatal development and adulthood reveals miR-483 as a candidate regulating muscle differentiation via IGF-1 signaling pathway. PLoS One 8(5): e62787.

Genome locations

Gene Ontology annotations

Sequence

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AAUCGUACAGGGUCAUCCACUU

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This sequence is found in 33 other species

  1. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-487b
  2. Canis lupus familiaris cfa-miR-487b
  3. Capra hircus (goat) chi-miR-487b-3p
  4. Cavia porcellus (domestic guinea pig) cpo-miR-487b-3p
  5. Cervus elaphus (red deer) cel-miR-487b
  6. Dasypus novemcinctus (nine-banded armadillo) dno-miR-487b-3p
  7. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-154-P17_3p (mature (guide))
  8. Equus caballus eca-miR-487b
  9. Homo sapiens hsa-miR-487b-3p
  10. Macaca mulatta (Rhesus monkey) mml-miR-487b-3p
  11. Mus musculus mmu-miR-487b-3p
  12. Oryctolagus cuniculus (rabbit) ocu-miR-487b-3p
  13. Ovis aries oar-miR-487b-3p
  14. Pan troglodytes ptr-miR-487b
  15. Pongo pygmaeus ppy-miR-487b
  16. Pteropus alecto (black flying fox) pal-miR-487b-3p
  17. Rattus norvegicus rno-miR-487b-3p
Publications