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Rattus norvegicus (Norway rat) rno-miR-93-5p URS0000149452_10116

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rno-mir-93: Rno-mir-93 is a microRNA that has been studied in various contexts. It has been found that the expression patterns of most miRNAs, including rno-mir-93, revealed by qPCR were consistent with deep-sequencing results, with only a few exceptions [PMC3441217]. Expression data from showed that rno-mir-93 is expressed in the embryonic and adult hippocampus, among other tissues [PMC4122175]. In the development of heart failure with preserved ejection fraction (HFpEF), several non-coding RNAs, including rno-mir-93, were strongly associated [PMC7667132]. Rno-mir-93 was found to be downregulated in the spinal cord of rats with chronic constriction injury (CCI), and its overexpression reduced the expression of Stat3 both in vitro and in vivo [PMC8914318]. The downregulation of rno-mir-93 and upregulation of Stat3 were implicated in the development of neuropathic pain [PMC8914318]. Additionally, overexpression of Stat3 reversed the repressive effects on neuropathic pain development and neuroinflammation induced by rno-mir-93 overexpression [PMC8914318]. The sequences for rno-mir-93 agomirs used were provided as well as a negative control for these agomirs [PMC6522868]. In summary, rno-mir-93 is a microRNA that has been implicated in various biological processes such as heart failure development and neuropathic pain. It exhibits consistent expression patterns with deep sequencing results and is expressed in tissues such as the hippocampus. Rno-mir-93 targets Stat3 and its downregulation contributes to neuropathic pain development. Overexpression of Stat3 can reverse these effects. The sequences for rno-miR-93 agomirs and a negative control were also provided [PMC3441217][PMC4122175][PMC7667132][PMC8914318][PMC6522868].

mRNA interactions 1 total

Genome locations

Gene Ontology annotations


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This sequence is found in 29 other species

  1. Alligator mississippiensis ami-miR-93-5p
  2. Bos taurus Bta-Mir-17-P4d_5p (mature (guide))
  3. Callithrix jacchus cja-miR-93
  4. Canis lupus familiaris (dog) cfa-miR-93
  5. Capra hircus (goat) chi-miR-93-5p
  6. Cavia porcellus cpo-miR-93-5p
  7. Cervus elaphus cel-miR-93
  8. Chrysemys picta bellii (western painted turtle) Cpi-Mir-17-P4d_5p (mature (guide))
  9. Cricetulus griseus cgr-miR-93-5p
  10. Dasypus novemcinctus (nine-banded armadillo) dno-miR-93-5p
  11. Daubentonia madagascariensis dma-miR-93
  12. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-17-P4d_5p (mature (guide))
  13. Equus caballus eca-miR-93
  14. Gallus gallus Gallus_gallus piRNA piR-gga-56021
  15. Homo sapiens (human) hsa-miR-93-5p
  16. Macaca mulatta Mml-Mir-17-P4d_5p (mature (guide))
  17. Monodelphis domestica (gray short-tailed opossum) Mdo-Mir-17-P4d_5p (mature (guide))
  18. Mus musculus (house mouse) mmu-miR-93-5p
  19. Nomascus leucogenys nle-miR-93
  20. Oryctolagus cuniculus (rabbit) ocu-miR-93-5p
  21. Otolemur garnettii oga-miR-93
  22. Papio hamadryas pha-miR-93
  23. Pteropus alecto (black flying fox) pal-miR-93-5p
  24. Sarcophilus harrisii Sha-Mir-17-P4d_5p (mature (guide))
  25. Sus scrofa ssc-mir1
  26. Tupaia chinensis tch-miR-93-5p
  27. Tursiops truncatus miR-93
  28. Xenopus laevis (African clawed frog) xla-miR-93-5p
  29. Xenopus tropicalis Xtr-Mir-17-P4d_5p (mature (guide))