gga-mir-1662: gga-mir-1662 is a differentially expressed miRNA that has been studied in relation to immune responses in chicken. It has been found to interact with TLR1LA, which is important in responding to SE infection [PMC5237128]. Following AIV infection, gga-mir-1662 was significantly up-regulated in chicken lung [PMC5237128]. Further research is needed to confirm the function of the interaction between gga-mir-1662 and TLR1LA [PMC5237128]. In the current study, gga-mir-1662 was down-regulated while its target gene TLR1LA was up-regulated in response to SE infection [PMC5237128]. Additionally, gga-miR-34a-5p and gga-miR-1416-5p were found to play important roles in SE infection through regulating their target genes [PMC5237128]. In a study comparing different miRNAs, including gga-mir-1662, it was observed that miRNAs in group one showed higher expression in the N group but lower expression in the I group [PMC5237128]. Several miRNAs have been identified as regulators of innate immune responses induced by S. Enteritidis, including gga-miR-155 and gga-miR-34a-5p [PMC8242174]. In relation to FAdV-4 infection, it has been reported that gga-mir-1662 affects immune responses by targeting IL24 and is differentially expressed at 120 min after infection [PMC7248314]. Overall, studies have shown that gga-mir-1662 and other miRNAs play important roles in SE infection by regulating their target genes [PMC6628503] [PMC6554294]