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Homo sapiens (human) microRNA hsa-mir-197 precursor URS00000F4AC3_9606

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MIR197: MIR197 is a microRNA that has been detected to change its expression in response to resistance training [PMC8505326]. It is one of several miRNAs that show immediate, 1-hour, 4-hour, and 24-hour changes in expression after a single bout of resistance training [PMC8505326]. MIR197 has been found to be inversely related to PD-L1 expression in acute myeloid leukemia, NSCLC, biliary epithelial cells, hepatocellular carcinoma, and colon cancer [PMC7529545]. It is considered a potential surrogate biomarker for PD-L1 expression in NSCLC [PMC7529545]. MIR197 levels have also been measured in sera using quantitative real-time polymerase chain reaction (PCR) [PMC7414326]. In the context of insulin resistance and glucose homeostasis, there appears to be an inverse correlation between glycemia and hepatic levels of MIR197 [PMC6197154]. MIR197 plays an important role in the maintenance of embryogenic callus in rice [PMC10049443]. In female breast cancer, up-regulation of MIR197 has not been reported so far [PMC2850898]. Changes in the levels of MIR197 have also been associated with metabolic syndrome [PMC8793096]. The DDB2 SNP rs1050244 may interfere with the targeted interaction between miR-133a and MIR197, resulting in upregulation of DDB2 mRNA expression and reduced susceptibility to HCC [PMC9712371]. Gap junction-transferred microRNAs including MIR197 have been shown to reduce cancer cell proliferation and induce dormancy that may lead to bone marrow metastasis relapse [PMC4699086].

Genome locations

Gene Ontology annotations


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This sequence is found in 40 other species

  1. Ailuropoda melanoleuca microRNA mir-197
  2. Aotus nancymaae (Ma's night monkey) microRNA 197 (ENSANAG00000003140.1)
  3. Ateles geoffroyi microRNA age-mir-197 precursor
  4. Callithrix jacchus (white-tufted-ear marmoset) microRNA mir-197
  5. Canis lupus familiaris microRNA mir-197
  6. Cavia porcellus (Domestic guinea pig) microRNA mir-197
  7. Cebus imitator (Panamanian white-faced capuchin) microRNA 197 (ENSCCAG00000005871.1)
  8. Cercocebus atys microRNA 197 (ENSCATG00000010166.1)
  9. Chlorocebus sabaeus microRNA 197 (ENSCSAG00000027418.1)
  10. Colobus angolensis palliatus miRNA (ENSCANG00000008210.1)
  11. Dipodomys ordii (Ord's kangaroo rat) microRNA mir-197
  12. Equus asinus asinus (donkey) miRNA (ENSEASG00005003016.1)
  13. Equus asinus (ass) microRNA 197 (ENSEASG00005003016.2)
  14. Equus caballus microRNA eca-mir-197 precursor
  15. Felis catus microRNA 197 (ENSFCAG00000016509.3)
  16. Fukomys damarensis microRNA mir-197
  17. Gorilla gorilla gorilla microRNA 197 (ENSGGOG00000041555.1)
  18. Gorilla gorilla microRNA mir-197
  19. Heterocephalus glaber (naked mole-rat) microRNA mir-197
  20. Lynx canadensis microRNA 197 (ENSLCNG00005014376.1)
  21. Macaca mulatta (Rhesus monkey) microRNA mml-mir-197 precursor
  22. Macaca nemestrina (Pig-tailed macaque) mne-mir-197 (ENSMNEG00000011353.1)
  23. Mandrillus leucophaeus (Drill) microRNA 197 (ENSMLEG00000005171.1)
  24. Microcebus murinus microRNA 197 (ENSMICG00000018023.3)
  25. Mustela putorius furo miRNA (ENSMPUG00000021421.1)
  26. Nomascus leucogenys microRNA 197 (ENSNLEG00000022265.2)
  27. Otolemur garnettii microRNA 197 (ENSOGAG00000018459.2)
  28. Pan paniscus microRNA ppa-mir-197 precursor
  29. Panthera leo microRNA 197 (ENSPLOG00000006482.1)
  30. Panthera pardus (leopard) microRNA 197 (ENSPPRG00000013967.1)
  31. Panthera tigris altaica microRNA 197 (ENSPTIG00000002677.1)
  32. Pan troglodytes microRNA ptr-mir-197 precursor
  33. Papio anubis (Olive baboon) microRNA mir-197
  34. Pongo abelii microRNA mir-197
  35. Pongo pygmaeus microRNA ppy-mir-197 precursor
  36. Propithecus coquereli (Coquerel's sifaka) microRNA 197 (ENSPCOG00000011865.1)
  37. Rhinopithecus bieti (Black snub-nosed monkey) microRNA 197 (ENSRBIG00000008109.1)
  38. Rhinopithecus roxellana microRNA 197 (ENSRROG00000027211.1)
  39. Saimiri boliviensis boliviensis (Bolivian squirrel monkey) microRNA 197 (ENSSBOG00000019454.1)
  40. Sciurus vulgaris microRNA 197 (ENSSVLG00005012919.1)
  41. Zalophus californianus (california sea lion) miRNA (ENSZCAG00015001604.1)