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Bos taurus (cattle) bta-miR-26b URS00000E73CB_9913

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bta-mir-26b: Bta-mir-26b is a microRNA that has been identified as a candidate regulatory gene involved in the negative regulation of intramuscular fat (IMF) deposition in animals [PMC6637853]. It was found to be downregulated in individuals with high IMF content [PMC6637853]. Bta-mir-26b is a member of the brown module, along with bta-miR-107, and these microRNAs have functions related to cellular processes essential for lactation processes or milk synthesis [PMC6164576]. The target genes of bta-mir-26b were investigated using dual-luciferase reporter vectors and co-transfection experiments in HEK293T cells [PMC9613354]. The ViTa algorithm identified additional miRNAs that could potentially target the genome, including bta-miR-205, bta-mir-26b, bta-let-7g, bta-miR-34a, bta-miR-144, bta-miR-181b, and bta-miR-147 [PMC5384155]. In a study comparing pregnant and cyclic states in the MC fraction of cows, both bta-mir-26b and another member of the same family were found to have significant expression changes [PMC5325256]. The binding capability of MSTRG.19263.1 (acting as a sponge for both bta-mir-26b and bta-miR378) to these microRNAs was investigated using dual-luciferase assays [PMC9613354]. BTA-MIRNA PCR Assay components contained primers for miRNAs including bta-mir29a, 200a, 26b, 27b, and 30b5p [PMC9961204]. Non-clustered miRNAs included let-7g, bta-mir-26b, bta-miR-150, bta-miR-34a, bta-miR-146a, bta-miR-147, bta-miR-205, bta-miR-4553p, bta-miR1224, bta-mir1281 and bta-mir31 [PMC5384155].

Genome locations

Gene Ontology annotations

Sequence

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This sequence is found in 20 other species

  1. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-26b
  2. Canis lupus familiaris (dog) cfa-miR-26b
  3. Capra hircus (goat) chi-miR-26b-5p
  4. Cavia porcellus (domestic guinea pig) cpo-miR-26b-5p
  5. Cervus elaphus (red deer) cel-miR-26b
  6. Cricetulus griseus cgr-miR-26b-5p
  7. Dasypus novemcinctus dno-miR-26b-5p
  8. Daubentonia madagascariensis (aye-aye) dma-miR-26b
  9. Homo sapiens (human) Hsa-Mir-26-P2_5p (mature (guide))
  10. Macaca mulatta (Rhesus monkey) Mml-Mir-26-P2_5p (mature (guide))
  11. Microcebus murinus (gray mouse lemur) mmr-miR-26b
  12. Mus musculus Mmu-Mir-26-P2_5p (mature (guide))
  13. Oryctolagus cuniculus ocu-miR-26b-5p
  14. Ovis aries (sheep) miscellaneous RNA
  15. Pan paniscus ppa-miR-26b
  16. Papio hamadryas pha-miR-26b
  17. Pteropus alecto pal-miR-26b-5p
  18. Rattus norvegicus Rno-Mir-26-P2_5p (mature (guide))
  19. Sus scrofa ssc-miR-26b-5p
  20. Tupaia chinensis tch-miR-26b-5p
Publications