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Bos taurus (cattle) bta-miR-27a-3p URS00000CCB2D_9913

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bta-mir-27a: Bta-mir-27a is a microRNA (miRNA) that has been identified as one of the eight miRNAs with functions related to mastitis, based on analysis of the RNA-Seq dataset GSE75379 [PMC8928958]. Among the differentially expressed (DE) miRNAs, bta-mir-27a is found to suppress the PSTPIP2 and VAV1 genes [PMC8928958]. Additionally, bta-mir-27a has been found to have nearly equal number of sequence reads originating from both the 5′ and 3′ arms of the miRNA hairpin precursor [PMC2713767]. Bta-mir-27a belongs to the miR-27 family, which also includes bta-miR-27b [PMC3589390]. It is worth noting that fhe-miR-2b-A and fhe-miR-2a-B are orthologs of bta-mir-27a and bta-mir-27b [PMC9861972]. Bta-mir-27a has variable abundance levels during placental development and is associated with trophoblastic differentiation and vascularization [PMC5662615]. Furthermore, both fhe-miR-2b-A and fhe-miR-2a-B have similarities with bta-mir-27a in terms of targeting specific regions in myostatin and insulin growth factor (IGF) genes in cattle and humans [PMC5390025]. References: [PMC8928958] - https://pubmed.ncbi.nlm.nih.gov/33708179/ [PMC2713767] - https://pubmed.ncbi.nlm.nih.gov/21460147/ [PMC3589390] - https://pubmed.ncbi.nlm.nih.gov/23533145/ [PMC9861972] - https://pubmed.ncbi.nlm.nih.gov/34616706/ [PMC5662615] - https://pubmed.ncbi.nlm.nih.gov/28916706/ [PMC5390025] - https://pubmed.ncbi.nlm.nih.gov/28235882/

Genome locations

Gene Ontology annotations

Sequence

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UUCACAGUGGCUAAGUUCCG

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This sequence is found in 22 other species

  1. Canis lupus familiaris cfa-miR-27a
  2. Capra hircus (goat) chi-miR-27a-3p
  3. Chiloscyllium plagiosum microRNA cpl-miR-27d-3p
  4. Gadus morhua (Atlantic cod) gmo-miR-27d-3p
  5. Mus musculus (house mouse) Mus_musculus piRNA piR-mmu-8319572
  6. Oryzias latipes ola-miR-27a
  7. Otolemur garnettii oga-miR-27a
  8. Ovis aries (sheep) microRNA miR-27a
  9. Pteropus alecto pal-miR-27a-3p
  10. Rattus norvegicus Rattus_norvegicus piRNA piR-rno-62965
  11. Xenopus laevis (African clawed frog) xla-miR-27a-3p
Publications