cfa-miR-30c: Cfa-mir-30c is a microRNA that has been studied in various contexts, including metastatic and non-metastatic mammary tumors, dogs with MMVD (myxomatous mitral valve disease), dogs with PS (pituitary-dependent hyperadrenocorticism), and heart diseases in dogs [PMC7646326] [PMC8062772] [PMC4768678] [PMC8542680] [PMC9607079]. In metastatic and non-metastatic mammary tumors, cfa-mir-30c was one of the ten microRNAs that showed significant differential expression [PMC7646326]. In dogs with MMVD, cfa-mir-30c was significantly down-regulated compared to healthy dogs [PMC8062772]. Similarly, in dogs with PS, cfa-mir-30c was significantly down-regulated compared to healthy dogs [PMC8062772]. In adrenal cortex samples, cfa-mir-30c was part of the cfa-miR-30 family and showed significant abundance along with other microRNAs such as cfa-miR-99a and cfa-miR-26 family [PMC4768678]. In a study investigating heart diseases in dogs, including cardiac hypertrophy, cfa-mir-30c was one of the 11 candidate miRNAs that were investigated using qRT-PCR [PMC8542680]. The study found that cfa-mir-30c was upregulated in the PDA (patent ductus arteriosus) group and PS group compared to healthy controls. It was also upregulated in the MMVD group compared to healthy controls. Additionally, when stage C and D heart disease cases were compared to healthy controls, cfa-mir-30c showed significant downregulation along with other microRNAs such as cfa-miR-375 and cfa-miR-19b [PMC9607079]. Overall, cfa-mir-30c has been implicated in various diseases and conditions, showing differential expression patterns.