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Homo sapiens (human) hsa-miR-3123 URS00000939AF_9606

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hsa-mir-3123: Hsa-mir-3123 is a candidate miRNA that has been identified upstream of the MMP9 gene [PMC6742920]. It is also predicted to potentially target the 5ʹUTR of the SARS-CoV-2 genome [PMC8527307]. Hsa-mir-3123 has been found to potentially target the SOCS3 gene, both in its 3ʹUTR and 5ʹUTR [PMC8527307]. However, its expression in human pancreas cells is currently unknown and requires further investigation [PMC8527307]. Hsa-mir-3123, along with other CoV-tar-miRNAs, has been found to target the CP mRNA in both its 3ʹUTR and 5ʹUTR [PMC8527307]. It is also downregulated in insulin receptor haploinsufficient hepatic stellate cells [PMC8527307]. Hsa-mir-3123, along with hsa-miR-4775, has been identified as one of the most influential CoV-tar-miRNAs that target upregulated Diabetes-associated genes [PMC8527307]. However, its expression in the human pancreas remains unknown and requires further investigation [PMC8527307]. Other Diabetes-associated CoV-tar-miRNAs have been found to be expressed in the human pancreas except for hsa-miR-466, hsa-mir-3123, hsa-miR-6749-3p, and hsa-miR-7851-3p [PMC8527307]. References: [PMC6742920] - Srinivasan S. et al. (2019). miRNA-based therapeutic intervention of cancer. Journal of Cancer Research and Therapeutics. [PMC8527307] - Kumar S. et al. (2021). Identification of potential miRNAs targeting SARS-CoV-2 and their role in regulating COVID-19 associated genes in human cells. Scientific Reports.

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