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Homo sapiens (human) long intergenic non-protein coding RNA 1447 (LINC01447) URS000008DBFD_9606

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LINC01447: LINC01447 is a long non-coding RNA (lncRNA) that has been implicated in various diseases, including hepatocellular carcinoma (HCC) and low-grade glioma. In HCC, a risk scoring system was developed using the expression levels of multiple lncRNAs, including LINC01447, to predict recurrence-free survival (RFS) [PMC9080350]. LINC01447 was found to be a protective factor for RFS in HCC patients [PMC9080350]. In low-grade glioma, LINC01447 was associated with poor prognosis and decreased overall survival (OS) and progression-free survival (PFS) after radiotherapy [PMC8268860]. Downregulation of LINC01447 enhanced the radiosensitivity of low-grade glioma cells [PMC7288909]. Additionally, LINC01447 was identified as one of the central node genes that might play crucial roles in radiosensitivity in low-grade glioma [PMC7288909]. Overall, these findings suggest that LINC01447 is involved in the progression and treatment response of HCC and low-grade glioma. However, further research is needed to fully understand the molecular mechanisms underlying its functions.

Genome locations

Gene Ontology annotations

Sequence

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GUGUUAAUCAGCUCAAUUAGACUCCCUUCCUUAUCACACGGACAGAGGGCUUUCUGUAUCCUGGGGUUUCUUGUCUUGGUGUACCGGAAGAAUUGGAUCAUGGGUGGGCUUGGAGAAUGAGUGCAAGGUUCUAUUGAGUAGAAGUAGCCCUCAGCAGAUGGGGGAGCCAGAAGGGAGAUGGUUUUUGCCUGCAGUCAGGCCACUUGGCCGCCCCAGCUCUCCUCUGACUGCUCCAGCCAAACUCCGCCUCAUUCUGCCAGUCGAUGGCCAGCAUGUCGGCAUCUGUUGAUGUGCUCUUCUGCUGGCAUGCUCCCUCGACGUUCUCUCAAUAUCCGGCCGCCUGUGUCUUCUUCUGCUGAUCUGCUCCUCUCCACAUCCAGCGGCUUGUGUGUCUGCCUGAUGAGGUCAGGAAGUGGCUAAGAAGAGAUCCAUGAAGAUUAACAUUCAGUGCUCAAUUUCUGAAGGAAACAGGGAGUGAAAGGCCGUGGAAGAAAACAGGGCUGCCACGAACAUGCUCUUGGCUGUUUGAAAAGAUCCAGCGCAGCUUGAACUUCAAAAAUAACUCCAUUCACUAUGGUUGCAGUUGGGCUUGGGGAAUUUCUCACAAUCAAAAGCAGCUGCUUCAUCUCAUUUAGCCAUUAGGCUGAGCUCCACAGGCUCGCUGCAGGAUCUUAGAGCCUACAAGGCCCUGCUAAGAGUAGCCGCGUUUUCCAGCAUGCAGUAGAUCAGCGAGUGUUUACAUUUGUGUUUGGAAUGCUCAUGAGUCCUUUGGGGCAAAGACUGAGUCAUUAAUCAGAGCUUUCUAUGAACGUAUUGCUGCCCAAGCCUCUGUGAAUGUGAGUACGGCCUUGUCCCCUGAGUGACGCUGAAAGAGAGUGAAGCACAUGUGCUCCAUAGGACUGCCACGGCCACCCCUCUCAUUCACUUUUCCAUUCAGCGCUGAGACUAAGUUUAACUCAUUUUUCUUUUGUUGUGAAAAGAGAAUGCACACAAAAAUUCAAAUGUUACCAAAUCGAUAUCAGGUUGGAAGCUGAUUCCCCUUGCCUGAGUCCGGGCUGUGUUUGGCGAUACUUGUAAAGAAUGGAAUCUGGCUGAGGUGGAGGUGUGUGACUUUGAGGACUAGGUCCAAAGAAGGCAUUGUGGUUUCCAUCUUGACUGCUCUUUCCCUUGGAUAGCUGACUCUUAGGGAAGCCACAUGCCACACCAUGAGCAGCUCUGCGGAGAGACCCAUGCAGCAAGGAAAUGAGGCUUCCAGUCAAGAGCUGCAUGACUGAAUGAACUUGUUACCAAAACACCAGGGGUUUGGUCCAGGUCCUUCUGCUCACCGCAUGGAAAGCUCAUCACUGAGAUGACAAGUAUUGCCAAGGAAGGAUUUAAUCAGGUGCUGCAACCGAGGAGAUGGGAGCUCAGUCUCAAAUCCAUCUUGCUGACCUACUAAAACGAGGGAUUUGUAUAGCAGGGAAGAAAUGAAACAAUGUGUAAGAAAACAGCAACUAGGGAGGGGCACGGAAGCAAUCAUGAUGAAUGAGGGGGCAGCAUCUCAUUGUCUGAAUGCGGUGAUCUGGCCUUAGCUGCCUUCCCGCGGGGCAGGCCUCGGGACUGCAGCCCACCAUGCCUGAGCCUUCCCCCUCCUCCGUGGAUUCCUGUGCAGCCGGAGCCUCCCCGACGAGCGCCACCCCCUGCUCCAUGGCGCCCAGUCCCAUCGACCGCCUAAGGGCUGAAGAGUGCGGGCGCAAGGCACCGGGACUGGCAGGCAGCUCCACCUGCAGCCCCGGUGCGGGAUCCACUGGGUGAAGCCAGCUGGACUCCUGAGUCUGGUGGGGCCUUGGAGAACUUUUAUGUCUAGCUCAGGGAUUGUAAAUACACCGAUCGGUACUCUGUAUCUAGCUCAAGGUUUGUAAACACACCAAUCAGCACCCUGUGUCUAGCUCAAGGUUUGUGAGUGCACCAAUCGACACUCUGUAUCUAGCUGCUCUGGUGGGGCCUUAGAGAACCUUUGCGUGGAUACUCUGUAUCUAACUAAUCUGAUAGGGACGUGGAGAACCUUUAUAUCUAGCUCAGGGAUUGUAAACGCACCAAUCAGCACCCUGUCAAAACAGACCACUUGGCUCUACCAAUCAGCAGGAUGUGGGUGGGGCCAGAUAAGAGAAUAAAAGCAGGCUGCCGGAGCCAGCAGUGGCAACCCACUGGGGUCUCCUUCCACACUGUGGAAAGUUUGUUCUUUCGCUCUUUGCAAUAAAUCUUGCUGCUGCUCACUUUUUGGGUCCACACUGCUCUUAUGAGCUGUAACACUCACCGCGAAAAUCUGUAGCUUCAUUCCUGAAGCCAGCGAGCCCACGAGCCCACCGGGAAGAACGAACAACUCCAGACGUGCCGCCUUAAGAGCUGUAACACUCACCGCGAAGGUCUGCAGCUUCACUCCUGAGCCAGCGAGACCACUAACCCACCAGAAGGAAGAAACUCCGAACAUCAGAAGGAACAAACUCCAGACGCGCCACCUUAAGAGCUGUAACACUCACUGCGAGGGUCCGCGACUUCAUUCUUGAAGUCAGUGAAACCAAGAAUCCACCAAUUCCGGACACACUAUCACCCAUGAAGAGUAGUUACUGUAACAUUGUAGCACACUGCAUUACUCAGGUGUUUGUGGGGUUGCUGAUGUGAACAAACCUGCAUGGCCAGUUGCAUAAAAGUAUAGCACACACGAUUAUGUACAGCCCAUAAUACGUGAUAGUGAUAAUAAAUGACUGUUACUGGUUUAUGU

Taxonomic tree

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Expression New Publications