Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) hsa-miR-526a-5p URS0000087207_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

hsa-mir-520c: Hsa-mir-520c is a microRNA (miRNA) that belongs to the miR-520 family [PMC5311252]. It contains a strong seed sequence homology with other miRNAs in the family, including hsa-mir-372, hsa-mir-373, hsa-mir-519c [PMC5311252]. Alterations in the expression level of hsa-mir-520c have been observed in isolated exosomes of patients with pancreatic cancer (PC) [PMC7762339]. Hsa-mir-520c is one of four miRNA genes that contain polymorphisms overlapping both the Drosha and Dicer cleavage site [PMC4299713]. It has also been identified as a prognostic factor impacting the survival of hepatocellular carcinoma (HCC) patients [PMC7150540]. However, the specific mechanisms and pathways involving hsa-mir-520c in HCC have not been determined [PMC7150540]. Hsa-mir-520c has been shown to have regulatory effects by binding to the 3'-UTR of amyloid precursor protein (APP) and negatively correlating with endogenous APP levels in HEK-293 cells [PMC9441681]. Sequence analysis has revealed a single point mutation in the stem loop structure of hsa-mir-520c in a cell line derived from a patient with malignant melanoma [PMC3544448]. Hsa-mir-520c belongs to both the "miR-302/372/373" and "miR-520" families of miRNAs [PMC5584237].

mRNA interactions 1 total

Genome locations

Gene Ontology annotations


No annotated location


Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

This sequence is found in 7 other species

  1. Gorilla gorilla gorilla ggo-miR-518d-5p (MIR518D)
  2. Gorilla gorilla (western gorilla) ggo-miR-520c
  3. Pan troglodytes (chimpanzee) ptr-miR-526a
  4. Pongo pygmaeus ppy-miR-518e-5p