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Homo sapiens (human) hsa-miR-377-3p URS000007F792_9606

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hsa-mir-377: Hsa-mir-377 is a microRNA that has been identified as a potential prognostic marker in various diseases, including cancer and diabetes [PMC9891867]. It has been found to be upregulated in response to PKCε activation, leading to downregulation of ADAMTS5 and a reduction in cleaved aggrecan in NP cells ECM [PMC3842981]. Hsa-mir-377 has also been implicated in tumour development, suggesting a potential role in cancer progression [PMC9891867]. Additionally, it has been identified as one of the differentially expressed miRNAs in PC3 cells [PMC6874298]. Furthermore, hsa-mir-377 has been validated as one of the miRNAs that can be predicted using training data unrelated to the original dataset [PMC1159118]. References: - [PMC9891867]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891867/ - [PMC3842981]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842981/ - [PMC6874298]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874298/ - [PMC1159118]: https://pubmed.ncbi.nlm.nih.gov/1159118/

Genome locations

Gene Ontology annotations

Sequence

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AUCACACAAAGGCAACUUUUGU

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This sequence is found in 24 other species

  1. Bos taurus (cattle) bta-miR-377
  2. Callithrix jacchus cja-miR-377
  3. Canis lupus familiaris (dog) Cfa-Mir-154-P6_3p (mature (guide))
  4. Cavia porcellus cpo-miR-377-3p
  5. Equus caballus eca-miR-377
  6. Macaca mulatta mml-miR-377-3p
  7. Mus musculus mmu-miR-377-3p
  8. Oryctolagus cuniculus ocu-miR-377-3p
  9. Pan troglodytes (chimpanzee) ptr-miR-377
  10. Pongo pygmaeus ppy-miR-377
  11. Pteropus alecto pal-miR-377-3p
  12. Sus scrofa (pig) ssc-mir31
Publications