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Homo sapiens (human) hsa-miR-208a-5p URS000005FEE9_9606

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hsa-mir-208a: Hsa-mir-208a is a microRNA that has been extensively studied in various cardiovascular disorders. It has been found to decrease in expression in heart failure [PMC9016216]. Among miRNAs specifically expressed in skeletal muscle, hsa-mir-208a is one of the myo-miRNAs that is significantly up-regulated in the plasma of trained subjects [PMC6367481]. The expression levels of hsa-mir-208a have been found to be associated with recurrence-free survival times, suggesting its potential as a prognostic marker [PMC6522811]. In terms of its interactions with other genes, hsa-mir-208a has been reported to have interactions with various DEGs, including hsa-miR-1, hsa-miR-124, and hsa-miR-133a [PMC6522811]. Additionally, it has been found to have 3' relationships with other microRNAs such as hsa-miR-129-3p and hsa-miR-129* [PMC2486268]. Hsa-mir-208a has also been implicated in large artery stroke samples and is up-regulated specifically in those cases [PMC3565366]. In terms of its detection and expression patterns, it has been shown to be undetectable in healthy patients but appears early after the onset of chest pain in acute myocardial infarction patients [PMC6406975]. Hsa-mir-208a is a cardiomyocyte-specific microRNA and was not detected in the serum at any time point [PMC5226070]. Overall, these findings highlight the importance of hsa-mir-208a as a potential biomarker and regulator of cardiovascular disorders.

Genome locations

Gene Ontology annotations


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This sequence is found in 6 other species

  1. Cavia porcellus cpo-miR-208a-5p
  2. Dasypus novemcinctus (nine-banded armadillo) dno-miR-208a-5p
  3. Macaca mulatta (Rhesus monkey) mml-miR-208a-5p
  4. Mus musculus mmu-miR-208a-5p
  5. Pteropus alecto (black flying fox) pal-miR-208a-5p
  6. Rattus norvegicus rno-miR-208a-5p