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gga-mir-30d: gga-mir-30d is a type of microRNA (miRNA) that is encoded on the second chromosome of chickens and belongs to the miR-30 family [PMC7125550]. Research has demonstrated that this miRNA plays a role in the immune response to infections by targeting specific proteins in cells. Specifically, gga-mir-30d has been found to inhibit the replication of Infectious Bronchitis Virus (IBV) in chicken macrophage HD11 cells [PMC8779696]. The mechanism by which gga-mir-30d exerts this antiviral effect involves the downregulation of ubiquitin-specific peptidase 47 (USP47), which is a protein that would otherwise be utilized by IBV for its replication [PMC8779696].
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