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Gallus gallus (chicken) gga-miR-30d URS000005CF5F_9031

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gga-mir-30d: gga-mir-30d is a microRNA (miRNA) encoded by chicken chromosome 2 and belongs to the miR-30 family [PMC7125550]. Research has demonstrated that gga-mir-30d has the ability to inhibit the replication of Infectious Bronchitis Virus (IBV) by targeting a specific protein called ubiquitin-specific peptidase 47 (USP47) in HD11 cells [PMC8779696]. This finding suggests that gga-mir-30d plays a crucial role in the immune response against IBV infection. MicroRNAs are small non-coding RNA molecules that regulate gene expression by binding to specific messenger RNA (mRNA) molecules and preventing their translation into proteins [PMC7125550]. The miR-30 family is known to be involved in various biological processes, including cell proliferation, differentiation, and apoptosis [PMC7125550]. In the context of IBV infection, gga-mir-30d has been identified as a key player in inhibiting viral replication. The mechanism of action involves targeting USP47, which is an enzyme involved in protein degradation and immune response regulation [PMC8779696]. By targeting USP47, gga-mir-30d can potentially disrupt viral replication and enhance the host's defense against IBV. These findings highlight the importance of gga-mir-30d as a potential therapeutic target for controlling IBV infection. Further research is needed to fully understand the regulatory mechanisms of gga-mir-30d and its potential applications in antiviral strategies.

Genome locations

Gene Ontology annotations


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This sequence is found in 20 other species

  1. Anolis carolinensis (green anole) aca-miR-30d-5p
  2. Capra hircus (goat) miR-30d
  3. Danio rerio (zebrafish) dre-miR-30d
  4. Equus caballus (horse) eca-miR-30d
  5. Gorilla gorilla gorilla ggo-miR-30d (MIR30D)
  6. Gorilla gorilla ggo-miR-30d
  7. Homo sapiens hsa-miR-30d-5p
  8. Macaca mulatta (Rhesus monkey) mml-miR-30d-5p
  9. Macaca nemestrina (pig-tailed macaque) mne-miR-30d
  10. Monodelphis domestica mdo-miR-30e-5p
  11. Mus musculus mmu-miR-30d-5p
  12. Ovis aries (sheep) miscellaneous RNA
  13. Pan paniscus (pygmy chimpanzee) ppa-miR-30d
  14. Pan troglodytes (chimpanzee) ptr-miR-30d
  15. Pongo pygmaeus (Bornean orangutan) ppy-miR-30d
  16. Rattus norvegicus rno-miR-30d-5p
  17. Takifugu rubripes fru-miR-30d
  18. Tetraodon nigroviridis (spotted green pufferfish) tni-miR-30d
  19. Tor tambroides (Thai mahseer) miR-30b
  20. Xenopus tropicalis (tropical clawed frog) xtr-miR-30d