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Homo sapiens (human) ZBTB20 antisense RNA 4 (ZBTB20-AS4) URS000001BC5F_9606

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ZBTB20-AS4: ZBTB20-AS4 is a long non-coding RNA (lncRNA) that has been rarely reported [PMC8927645]. In a study exploring m5C-related lncRNAs in low-grade glioma (LGG), ZBTB20-AS4 was identified as a prognostic biomarker [PMC8927645]. The study utilized univariate Cox analysis to select 81 differentially expressed prognostic-related lncRNAs, including ZBTB20-AS4 [PMC9334800]. Another study identified ZBTB20-AS4 as one of the five lncRNAs that intersected between differentially expressed lncRNAs in colorectal neoplasia and prognosis-related lncRNAs [PMC8987889]. In the same study, ZBTB20-AS4 was found to be a risk factor for poor overall survival in LGG patients [PMC8927645]. The expression of ZBTB20-AS4 was significantly increased in LGG samples with 1p/19q co-deletion and IDH mutation, which are clinicopathological features of LGG [PMC8927645]. Furthermore, ZBTB20-AS4 was found to be differentially expressed in various tumors, suggesting its potential conservation in tumor progression [PMC8927645]. In a model that included seven lncRNAs, ZBTB20-AS4 was one of the identified biomarkers for predicting overall survival in patients with non-small cell lung cancer (NSCLC) [PMC9226973].

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