mmu-mir-691: Mmu-mir-691 is a significantly differentially expressed miRNA that is upregulated in various conditions, including ulcerative colitis (UC) and immune defense against PM2.5 intratracheal instillation and virus infection in mice [PMC5819906] [PMC8291871]. It has been shown to bind to the IL-25 3'UTR, leading to reduced expression of IL-25 in UC [PMC9901255]. Mmu-mir-691 has also been identified as a host miRNA involved in modulating H7N9/AH1-PB2-627E/701N virus replication [PMC7399063]. The specific binding sites of mmu-mir-691 have been identified in circRNAs, suggesting its role as a 'miRNA sponge' [PMC6657977]. RT-qPCR assays have confirmed the upregulation of mmu-mir-691 in the intestinal tissue of UC mice, indicating its potential role in protecting against gut inflammation [PMC8291871]. However, the exact function of mmu-mir-691 and its role in UC are still unknown [PMC8291871]. Overall, mmu-mir-691 is an upregulated miRNA that has been implicated in various biological processes and diseases.
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