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hsa-mir-660: Hsa-mir-660 is a microRNA that has been studied in various contexts. In a study comparing kidney tissue samples of patients with membranous nephropathy and healthy controls, hsa-mir-660 was found to be upregulated [PMC8610666]. It was also identified as one of the co-downregulated miRNAs in another study [PMC9428793]. Hsa-mir-660 has been implicated in various diseases, including cancers and nephropathy [PMC9952540]. In a pilot study, hsa-mir-660 showed a significant fold change between relapse patients and their controls [PMC4784328]. It has also been found to regulate the expression of target genes involved in diseases such as BMP6, GPX3, and VPS8 [PMC9777571]. High expression of hsa-mir-660 has been associated with high survival rates in certain patients [PMC6668497]. Hsa-mir-660 has also been linked to islet function and showed sex differences in expression levels between male and female donors [PMC4256841]. Additionally, changes in the expression patterns of hsa-mir-660 have been observed after exposure to low and high doses of X-ray radiation [PMC3424689]. Hsa-mir-660 is clustered with other microRNAs on the X chromosome [PMC5698490]. In liver cells, hsa-mir-660 was found to be upregulated along with other microRNAs such as hsa-miR-488 and hsa-miR-590-5p when HBx protein was expressed [PMC5352919].
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