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Homo sapiens (human) HOXB cluster antisense RNA 2 (HOXB-AS2) URS00021231B1_9606

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HOXB-AS2: HOXB-AS2 is an upregulated long non-coding RNA (lncRNA) that is part of the HOXB cluster genes [PMC8277837]. In a study on asthma, HOXB-AS2 was found to be differentially expressed [PMC8277837]. Additionally, HOXB-AS2 has been reported to be abnormally expressed in the epicardial adipose tissue in atrial fibrillation [PMC8335165]. In ovarian cancer patients, a signature of seven immune-related lncRNAs, including HOXB-AS2, was associated with poor prognosis and identified as independent prognostic factors [PMC8335165]. Pearson correlation analysis revealed significant correlations between different HOX antisense transcripts (HOXATs), including correlations involving HOXB-AS2 [PMC8602076]. The 18 identified lncRNAs in the clusters encoded by homeobox (HOX) genes are located in four clusters: the HOXA region, the HOXB region, the HOXC region, and the HOXD region [PMC8602076]. Furthermore, in a study on colorectal cancer patients, six lncRNAs were positively associated with overall survival (OS), including HOXB-AS2 [PMC7803494]. Overall, these findings highlight the involvement of HOXB-AS2 in various diseases and its potential as a prognostic marker.

Genome locations

Gene Ontology annotations

Sequence

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CUUAAAGAACAGGUAAAAAUUUAAAUCUAGAUUGGAGGGACAGGGAGGAAGAGGUGAGCAAAGGCAAGGAAGGGCGGUGAAGUUCACAGCUCCCCCCAUACCCCACUAGUGAACUAUUAUGCUAAUAUGAGAAGUAGUAUUUGGAGGCUGAGUCAAAGGCAGGCCUGGCCCGGGGGUGAGGGUGCCGGGUGCCCCUCUGCACUCAUUCGCAAUUGGAACACCAGGACUUUUUUAGAAAGUAGUUCUGGGUCUCCAACCCUCACACUCUGGCUCCCUCCUUCUGAGUCUCCAGCCCCGGCUUCUUCCCUCCACUACACCCUCUCUAUUCCUCCCAAAUCUCCCUCCAGUCUCCAGGCCCAGUCUCUAACCAAGGGAGAGGGAAAGACCAGAACUUAAAAAAAAAAAAAAAAAAAAAACACCCCUCCCCCUUUUUCUUUUUGAGAACAGACAACAAGCGGUGAGUGAUGAUUUUAAAAACUCUGAACAUCUUGCAGGGGGAGGAGGGUUGAGAAAAGGGUGACAAAAGGAGGACUCUGUGUUUUAGUUUGAGCUCCAGACUGGCUGGCAGUAGACGGGCUGAAAGAACUUCAUGGAUAAGUUUCUGUUAUGAUUCUCACCUCCGAAUAGGCAGAAGGGGCUAAGAGGUGAUAAGGACAUUUGUACUUCUAAGAAGAGAAGAACUAGCAGGGUCGCUUAAUUUUAAAUGCACUGGCAGAAGAGAUGGAAGAUGGUUAUUAUUAUUAUUCAGAACAACCCUGUUUGUUUCUCUCUGCCCUGCAAGAUUUAUGACUCUUGGCACAAGUGAGGAAGGCCACAAAAGCUAAAGUUUUCUUAGGGUGUGUUUGAGCAGGGCAGGAAAAGGCAAGGAGGAGGCCUGUAGGAGGAAGACAGGAGCCAAAAAUGUAGGUGUCUGCAGAUUUGGGACAGGGGGUGGGGAAUAGUCAUUCCGGGAGGAAGGAAAAGACAAAAAGAGCACCAGGACAUUUCCCAAAGCAGGAGUGUUUGCAACUCUGCCUAACUGCUGACUCGGAGCUAGGGGAUGAAAUAGAAAGCUGACUCUUUUCUCUAAAGGCAGCUUGGAAAACUGGUCCUCUUAACUUCAUGUAAGGCACUACCCUGUGAUUUCCUGGUUAGAAUACUUGGCUUUUGCCUUCUCCCAUCUGGAUGCACCAGAAGAGGGAACGGGACUGGGGACAACAAAGUAUUAACGAAGAUUUCAAAGCUGGGAGUUGUAAAGUGGGAAUUGCUAAUGAAGAAGGCUCUUGGCAUUUGGAUCCCCAUCUCCAGCUCUCCAAUAAGCCAGAGCAGGAGGGAACAAAGGGGCACCCGGAAGGGAGAAGAGGAGACUCGCAUAGACACUGCUCAGCAAUAGUGGGGAUCAAAAGAAGAAAAAGGUCGCUGCAGUGGAAGAAGAAAAAUCCAAGCUGUACUUUUUCCCCACCCCACGUGUGGGGGCGCUGCCCUCUCCCCAGCUGAGCCUGUGAAGGGGUGGCAGGACAAAAAGGGCAGCCACAAGGGUCUGCGAAGUCCACUCGAUGACCACGGAGGCCGCCUGAACAUGCUAAUGAGGGGAUGGCGGUGCUGCCAGCGAGUUGGGAGCCUCAGGCAGGUGGGCUCCUUGGUGGUGAUAGAUCCCAAUCUGAAUCAGGGCUCCCGCCUCACCUAGAAGCUCAGCCUUAGCCUGGCAAACCCCACCCCCAGCAAGUGUUGAGACAAAGGUGGGCAGAGCAGAGAAGGCAGAGGAAGGGAGGCUGCAAAUCCUGGGCAGCUUGGGGGCUGCAGGGGGUGCUGGGAAAGGGAGGGAGAAGCAGGAAAAGAGGAACGGGCCCAGUCCCUGAGGUUCAGCGGGCCUCUCCUGACAGACUGGAUGUUUCUCUCCCAGUGACCUCUGUUUAGCAGACAAUAACUCAGUGGAUUAAUGACCAAUCAGCGAAAGGCCUUCCGAAUUGCCUCCAAAUAUAAAACUCCGAAGUCAGAAUGGGACAGAGCCAGAGUCUGGGCCUGCCAGCUCUUUUGUUUUUUUUUUCUCUCUCAAAUUAGUGUUUGGGGCUAGGCUUUAGGAAGUGGAUUAUCUGCCCAGUGUCUCAGAUUUCCAGAGCCCCAAAGAUGAGGUUGUUUCCCAUCUCUUCCCAUCUUCUUCUUCCCUCCUUCCCCGGAAUUCAUAUUCCAAACCACACUUCCCAAGGCAGCCUGGAAACCUCCCCUCCCCUGCUAGCCUCUUCACAUCCCUGAUCCUGCAAGAAAUUUCCUUGCUCACAACCAUGCAAUUGAGAAGCCACCACUCCUUUGGAACUGGGGGAGGAGCUGGAAAAUAAAAGCAAGUAUAGAGUGGGAGUCUUCCACCAUGCAGGCCUUCUGUCCUGGCUACCCUAGAGGAGACCCGGUAGAGUGCUGUGGCACCCUGUGUGUGCUUCCUCCCAAGAAGCCAGGGCUCAGAGGCCCAGGGUUGGGGUGAGGCUGAGAAGGGAGGCACCUGCUAUCACAGAAUCUAAACUCUGAAACCACUGUUCAGUCCCUGGGCUGGGGUAGGGGGCACCUUAAAAACCACACUCUGUUGGGAGGCCGAGGCAGGCGAUCACCUGAGGUUGGGAGUUCGAGACCAGCCUGACCAACAUGGCGAAACCGUGUCUCCACUAAAAAUACAAAAUUAGCCAGGUGUGGUGGCGCAUGCCUGUAGUCCCAGCUACUCGGGAGGCUGAGGCAGGAGAAUCGCUUGAACCCAGGAGGCAGAGGUUGUGGUGAGUGGAGAUUGCACCAUUGCACUCCAGCCUGGGCAACAAGAGCGAAACUCCGUCUCAAAACACACACACACACACACACACACACACACACACACACACACACUGAACAAUGACAGCCUUAGCCCAGUGCCUGGCAGGGAAAGACUCUUGCUCAGUAAGGCCCAGCCCUUCUUUACUUAGCCCUUCUCCAAAUGCCAAUCUCAACCCAACCCAGCUAGCUGGCCCCUCACCACUUCCUUCUAGUUCCACUGCUCUCCUCAGGGCUACUCCUCAGCUGAGAAUAAGGGCACCUUCAGAAAGAGGAAUAGUCCAGAUUCCAGUGGAUUUCCUAGAGCCAGACUGAGUAAGCAUCCACUGCUCUGGGUGUAUGUAAACUCUGAAUAUUGCAAAUAAACAUGCAGUAACUUCUAUACCCAGAUGCCCACAGAGCUCCAGGACACACAAGGGAGUGCCUCCCAUGCACUGUCCUGCUGAGGAUGGGUACACACAGAGGUGCCCAAUUUCAGAACAGGAGAGAAAUCAGGAAGUGUCCAGUCCAACUCUUGCCAUUGUUACAGAUCAGGAAACUGAGGCCCAGAGCAAGGAAGUGAUUUGUCUAGAGUCAUACUUGGGAUAGGCUUGGGAGUUGGAAGGCCUGAAUUUCAGAUGUUCCAGCUUGGCUAUGUGACAUGAGGCAGGGCACUCCUUGGGCCUGAGUGUCCCCUUCUGUAAAGCCUGGGCAUGUGUAUGGAGGGAAGGGGUUUAGCUAAAUGAUCUCUAAGGUCUCUUUUUGGACUGAAUGUUAGUGAUUCUCCAUGUGCUGAUGUAAAAGUGAGUGACAAGAAGUAAUAAACUGAGUUCAGACAAUAACGGG

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Publications