v24

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Homo sapiens (human) CDH18 antisense RNA 1 (CDH18-AS1) URS0000BC4519_9606

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CDH18-AS1: CDH18-AS1 is an antisense RNA that is expressed in the testis and brain in human adults [PMC6483969]. Functional annotation of the target region revealed the presence of two long non-coding RNAs (lncRNAs) and CDH18-AS1 [PMC6483969]. The CDH18 gene variation may play a regulatory role in other tissues during early human development [PMC6483969]. The SNPs rs4866180 and rs6884961 are located in the center of CDH18-AS1, downstream of the GWAS top SNP [PMC6483969]. These SNPs act as cis-eQTLs for CDH18-AS1 in human testis, but not in brain [PMC6483969]. Further laboratory experiments are being planned to investigate the impact of knockout or overexpression of cadherin 18 and CDH18-AS1 on metabolic processes in vitro [PMC6483969]. Reference: [PMC6483969] - Weyrich, P., Machado, Y., & Lin, T. (2018). A cis-eQTL genetic variant located downstream of a gene determines its antisense long noncoding RNA partner. Genome Biology, 19(1), 27. doi:10.1186/s13059-018-1406-y

Genome locations

Gene Ontology annotations

Sequence

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GGGGCUGAGGGCGCUCGGCCGCUUCCGGUCCUGCGCUGCGGGCCUCAGAGGACUUGGUGCUCGGCAAACCCAGAGACUCAAACGCCAUGUCCGGGGGGUGGGGGGAGCGGCGGUAGGGGAGAUCCUCACGCUGUGUUCGGCAGCGAGGCGGCGAGACGCGCCGGUUCAGCCGGAGACCGCUGUGGGAACCGCGCCGAACACGCUUUGGGCGGCCAUUUUGUAACUCGAAUCUACCCCCAAAACCAAUUCGAAAAAAAGGGAGGAAAGAAACGCCCCGACAGUGUUCUGAACUGGGUUGAACACACAAAGGAUGCUACAAUUUUCCACUUGUAUACAGGUCCCUCCAAGACUUCGCUUCUCACCAUGAUUCUGACAUUGAUAUGAAAACACACAAGAUUUCACUUCUCACCAUGAUUCUGACACUGAUAUGAUCACUGAAUGACCGUUUUCAGCAAUUCGGGCCUAUAAAAGUGUGAAAUAGAUUUUUUUUGAAAGUCCUAUUGUAUAUUCAAAAUUCUGUAACACUAGUGGUUUUCUUCACCUUGUAGCUUAUUAUGAUAAGCACUAAUUUUGACUCUGACAUUUCAACAGGAGCACUUAGUUAUAGACAACCAGGAAUGUUCAAGAAUGACUCAGGAGUAUUUUAUUGACAAGGUAAUCUUUGAGACCAGGGGGUCCUCCUCCCCCCAGCUGGAGGAAUUACACCUGGGCCCAACUUCCUGAAGUCUCAAGGUGGAAUAUAUCUGGUAUUCUUUGUAACAUAUUUCAAUAUUCAGUAGCCAAGUUCAGGCUAUUUCGUGCCCAAAUAUAUAUUGUUUUUCUCUUAUUUAUAAGAACAGUAUUAAACUGUCCCUAUAAUAUUAGAAAAGAGAAGAAGGGUCUCUUCACUGGAAGAGAAUAUUACAGAGUGUUCAGCCUUAAGUGUUUUCAGGUAUGCUUCAAGUCAAGCAUGCUUCUCUAAAGGUGAUUUAGACAAUGAGGUUCACAGGCAAGUAAGCCCUUCUGCCUACAAGUUGUGGCCUGUUUUGAAGAUUGUUUUUGUUUAGCCAAGCCCUUUAUGUGGCAUACUUAUCUGAGCUUACUUCUAAACACAAUUAGUUGAUGUCUAUAAAAAAAAUUUGAACUCGAUCAUUCCUGGAAACUUAUUUAAAAUGUAAAUAUAUAACUGGAAUUCUUAUUCAAAAGUUAUGUACUUCUUCAUAUUUGGUCCCAAUAAGAGCAGGGUAUUUGUUAUGUUUUACUCUCAGAAUUGACACAACUUAUUUCCAUCUUCCACUACCCUCAGUUUCUUUAACUAUAUCAUCUACUUUGUCUUUUCACAAUUCUUAAGUGAGAUUAUUGAUUUUUCUUUUUACUUCUUGUCAACUCUUUGCUGGUAAGAAUAGACAUAUAAAAUCAUUCUUGUAAUAAAAGGUCAUUCCUGGUGAA

Taxonomic tree

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Publications