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Homo sapiens (human) long intergenic non-protein coding RNA 1525 (LINC01525) URS00007E3714_9606

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LINC01525: LINC01525 is a gene that has been associated with white blood cell (WBC) traits [PMC8674726]. It is one of the five genes, along with LOC126987/MTCO3P14, GAPDHP32/HSD3BP3, FLG-AS1, and TRK-CTT13-1/MGST3, that have been reported for the first time to be associated with WBC traits [PMC8674726]. In the context of prostate cancer (PCa), LINC01525 has been identified as a novel partner gene to ERG [PMC9434886]. Specifically, in African patients with PCa, LINC01525 was found to be involved in a translocation with ERG [PMC9434886]. Additionally, LINC01525 was identified as one of the novel PCa partners to TMPRSS2 in African-derived fusions [PMC9434886]. Furthermore, LINC01525 was involved in a translocation with TMPRSS2 and an inversion with ERG and TMPRSS2 in UP2103 tumors [PMC9434886]. These findings highlight the potential role of LINC01525 in PCa development and its association with genetic rearrangements involving ERG and TMPRSS2. Overall, LINC01525 is an important gene that has been implicated in WBC traits and its involvement in prostate cancer warrants further investigation.

Genome locations

Gene Ontology annotations

Sequence

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AAGAAAGCCAUUCUCUGAAACCUUUCUGGGGCUGGAGCACUUGUCAAGAGUAAACAGAAAAGGAAUAAAGCUUGCCUCUUUUUUUGAAAAACCCAGCUGGACAAUGGGCAUAUUCAAUGGCCAAGGCCUCCUCUAAUUGCUGGCUUGGGAAGAACUGGAGAUAACUCAGCAAUGGAGAGACAAGGAGGGCUCCUAGGGAACAACUUGGAGACCGAGGAAUCUUGCUGAAUGCCAGCAGAAAAUCUGGAAGCAGAGCCAGUAUAAUUCAGCAUUACUGAGCCCACUGAGCUCUCCAGGGAAGUAUAAAUUGAGCACAGAAGCUCUGAAAUGGAUUGUAACCACAACAUCAGAGGUUAUAAGACCCUCAUUCCAGAGUGGUACUGCCCUGCGUCUGGGAAGAAGGAAGGCCACACAGAGAGACCAAGAAGAAUCCUAACAGACAGGGCUUGCUUGGUUUCCCCCUCAGUCUCUUACCGUUAGAUCAGACCUCUUUGGUCCUACCACGUUUCUACAUGGCUGUCCAUUCUUCAUCGAAUCUAAGAAUAAAAAUGGAUAGUUUUCCCUGAAAAAAAAAAAAAAA

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Publications