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Homo sapiens (human) long intergenic non-protein coding RNA 1711 (LINC01711) URS000075DF8A_9606

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linc01711: LINC01711 is a long non-coding RNA (lncRNA) implicated in the prognosis and progression of esophageal squamous cell carcinoma (ESCC) [PMC9092832]. It is one of six high-risk lncRNAs identified in a prognostic model for digestive system cancers, suggesting its potential as a biomarker [PMC9092832]. Functional studies have demonstrated that the knockdown of LINC01711 in ESCC cell lines leads to increased apoptosis and decreased proliferation, migration, invasion, and overall cell growth [PMC8877069]. Conversely, LINC01711 can promote tumor growth when introduced via exosomes in vivo [PMC8877069]. Mechanistically, LINC01711 serves as a competing endogenous RNA (ceRNA) that sequesters miR-326, thereby modulating gene expression post-transcriptionally [PMC8386530]. The presence of LINC01711 in bodily fluids has been proposed as a non-invasive diagnostic and monitoring tool for ESCC patients, which could streamline the diagnostic process and enhance its efficiency [PMC8386530].

mRNA interactions total

Genome locations

Gene Ontology annotations

Sequence

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UACAGGAAGUCAAGGUCAGGCCAUACCCACCACAGUUCGGGCAGCCAUAGAGGAGAGCUUUCUUAACGGUCCGCUGGGACCCAAGUGGGCCUCCCCUGGGACUGCGUGCUCCCCUACAGAACCUGAUGGCUGGAAACACUCACACUACUGCCUGUCCCGGCAUCUCUCCCUCCGCCGCAGGGGCUGAUGCUGCCACAGGACACAGAGCAGCAGGCCCCAGAGGCUUCUCUGCACCUCUGCUGCCUUUCUGAGUAAUCAGAGGAGGCCACACCCACUCCAGGACACCCACACGGGCCUUCUGGGCGAUGACGCUCCUGGCCCAGGAGUGGGGGGCUGCCUCACACCUGCUGCUGUGGGGCAGAGUCUCUCCUGGGUCGGGGCCUCGCUGGCGGAUCUGCUCCAUGUCGUGUGAUGUGCUGCAGCCCCGCGUCACCGAGAGCCUCUUAUGGGCCACCAAGUCCACACAGCCACUGGCCAUGGGGCACCCUGCAGGGCCUCUGGACACGGAGACCUGUGGUUCUCAGCCAGUGGUGAUUUUGUGUCCAGGGAACACCUGGCCAAGUCUGGGUUCAAUUUUGUUUGUCACAGUUUAAGGUUGGGGUGUCACUAGACAUCCUACAGUGCACAGGACGGCCCCACAGCAGACCAGCCCGACUGUCAGCAGCACCGAGCCGGGAAAGCCUGGUCUGGAGCCGUUUCUCUCUAGGGUCCCUGCUAGGGAACCCCUCACUGCCAUGGAGAACCCCUCUCCUCCUGUCUCUCAGGACUCUCCGAGGGUCAAGGAUGGAUGCCUCCCCAUCGAGGGCCAAACAAACUGACAAAUCGAGUGGGCAAACGGCUUACUCAAAGGCCAGGAGCAGCUACCCGAUGACUGCUCCCUCGACCUCUCUCUUCUCACUUUCUUCCCUAUUCCAUCCUUUGAUGGGUGGCCUGUUACACGUUUGGAAAUAAAAACAAGUGGGAAAGAAAAAAAAAAAAAAAAAA

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Molecular Relationships

 Publications