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Homo sapiens (human) NAPA antisense RNA 1 (NAPA-AS1) URS000075DEA4_9606

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NAPA-AS1: NAPA-AS1 is a long non-coding RNA (lncRNA) that was identified in a study that analyzed the expression levels of various RNAs in ischemic stroke patients [PMC8990852]. The study found that the relative expression of NAPA-AS1 in the ischemic stroke group was significantly higher than that in the control group [PMC8415716]. Additionally, NAPA-AS1 was found to interact with miR-24-3p, along with three other lncRNAs (KCNQ1OT1, SND1-IT1, and LINC01001) [PMC8415716]. These interactions may play a role in regulating LPAR3 and ADORA1 in ischemic stroke [PMC8415716]. The study also identified other RNAs that showed differential expression levels between the ischemic stroke group and the control group. For example, SND1-IT1 showed significantly lower expression levels in the ischemic stroke group compared to the control group [PMC8415716]. On the other hand, miR-24-3p and miR-93-3p showed significantly higher expression levels in the ischemic stroke group compared to the control group [PMC8990852]. Overall, these findings suggest that NAPA-AS1 may be involved in regulating chromatin and nucleosome assembly during ischemic stress. The study highlights NAPA-AS1 along with KCNQ1OT1 and LINC01001 as potential players in this process [PMC8415716]. Further research is needed to fully understand their roles and mechanisms of action.

Genome locations

Gene Ontology annotations

Sequence

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AGCUGCCGGCGUUGCCCUCUCCCAAGAUGGCGGCCAGGUCGCCUGCUCGGGCCUCCCAGGCGACUUUGCCCCACUGCGCCCGCGCUCUCUUCUCCUUUCCAUUUCUGGACCAAGGGGCUGCCAUAAGGAGUCUGUGACUAGAGAUGGGAGGUGGUGGCCACGGCCUCUCGCUGUAUGCUGUGUGGAAGGUCGAAUCAUCAUCAUCAUAAAACUUAAUAUUGCCCUUAUGUGCCAGGAACUACUAUCUCAGCAAUGGAGAUGUGGUGCUUGGCCGCAAUCGUGAAUCGGCCCUGGAGGGGACACAGGAAGGGGCUGCCUGCGACUCAUGACCUCCUGCGUGCCUGCCUGCUGACCUAUGACCCUUCAAGUUCCCACCCCUCAGCCACGCCUGUGAGGAGGGUCUUGUUUUGUCGCCUACGCUGGAGUGCAGUGGUGUGAUCACAGCUCACUGCAGCCUCAACUUCCUGGACUCAAGCGAUUUUCCUGCCUCAACCUCCCAAGAACUAGGACCCCAGAUCCCCAUGGACAAGGCACUUGCAUGAAUUGUGAGGCUCAUGGAGUUGGGGUCGGACAACACAGAGCCGGCUCCCUCCAGGAGCUGCAUGUCCAGAGAGGGAAACAGGAUGUGGACAGCAAGAAUGAAUACAUGCAGACCA

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Publications