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Homo sapiens (human) MIR762 host gene (MIR762HG) URS000075DE18_9606

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MIR762HG: MIR762HG is a long non-coding RNA (lncRNA) that has been identified as a potential biomarker for ovarian cancer and HER2-positive breast cancer [PMC6558455] [PMC8262145]. In ovarian cancer patients, higher expression levels of LINC00511 and LINC01132, as well as lower expression levels of MIR762HG and RP11‐83A24.2, were associated with poorer outcomes [PMC6558455]. In HER2-positive breast cancer, MIR762HG was one of the six core lncRNAs identified in a multiCox model with high-risk assessment capability [PMC8262145]. MIR762HG was also found to be closely associated with AC010595.1 and AP000904.1 in the ceRNA network, suggesting their joint involvement in the growth and metastasis of HER2-positive breast cancer through ceRNA mechanisms [PMC8262145]. The low expression of MIR762HG was associated with worse overall survival in HER2-positive breast cancer patients, indicating its potential role as a tumor suppressor gene [PMC8262145]. Furthermore, MIR762HG was found to be co-expressed with THUMPD3-AS1, CRNDE, hsa-miR-29a-3p, GINS1, and GINS2 in various correlations [PMC9462653]. These findings highlight the importance of MIR762HG as a potential biomarker for ovarian cancer and HER2-positive breast cancer.

Genome locations

Gene Ontology annotations

Sequence

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CCUUUGUCUCCGCGGAGCGUCACAAAGGUUGGAAGGGUCGCGGGGCCUCUGGGUGCCGAGCUGCAGAUGCCUCCACUGCGAGCACAGCCCUGAGACAAGGGCCCAGGCGCCCAGCGGGGCUGGUUUCACUCAGUCCAGCCGCACCUACCCGUGCCCUCACCAGAUCUUAAGAUACAGACAUUAAAACCUCCACCGGGCCGCGGCACAGGACAGCAGUUUUACUUUCUGUUUUUGGCAUUGCAUUGCCUCCAUUUCCUAGAGUGCACGUAAUAAAUACCGCUGGUGAUUCCAAAAUAUAAAGGUUGAAAAUAUUUACUUUACAAAAAUUUGGUUCCCAUACUGCUUUUAAGGCCAUCCUCUGCACUUGGUUCCCGCUGCUCCUGAUGUGGUUGAAAGAUGGAUGACCCCAAAGACGAGGAAAAGAUUAUUGGCUCCAUUUUUUAGAUGCGGCAGCCAGCUAAGGUCUAGACAGGGGAAGGGACUUGCCCCAAAUCACAGUUAGAGCAAAUCAGUCUGAAUCAGGAAUAACUCCAUUCCUAUCCCGCAUCCUGCCCUUUCACUACGCCACAGCUGCCUGGCUGCCUGGAGGAACAAAGGAGGGCCGGGCAAGAACGCCAUUACCAACUGCAAAUCCACAGGCAAAUGCAAGAGGACAGAAAUCCCAAGAACCCAGCCCCUAAGCCUUCAGCUCUGUCCCAGGUCUGCCUCUCCUCCAGGCCCUCAGGACGCAGGCUCCAAGCCUUCGACUGCCCAGAUCCCCCAUUCCCUCCAAGACCCAGGAGUCCAGCCUUCUGGCCUCUCUCACCUCAGCUUCCAGCAGUUCUGGAACAGGCUCCUCCUUGGUCAGCAUUGGGGGUUCGUCGGUGCUGCCAGCAGUUAUGCCCCCGGGAUCUGGAACGUCAAGGCGCUGCGAAUACGAGUGGGUCUCCACCACCAGAAUGGCUAAAGUGAAAAAGACCGCACCGUGUGGAGGCGAGAAAGUAGAGCGACUGGACCUCUCUUGUAUUUCUGGGGGAGUGUAAAUUGGUAGAGACAUUUUGGAAAACUGGCAGUUUUCUAAUGAAGCCGAACAUAUGCCACCUCUGUGAUCCAGCAGUUCCACUCCUAGGCUGUCAACACCCAGCAGAAAUGUGUAGGUGUGAGCAUCAAGAGGGUGCAUGGGAAUGUUCAGAGCCCUUUCAUAACAGCCCCAAACUGGAAAUAACCCAUCAACAGAAUGGAAAAUGAAUGAUGCCCUACUCACUACCAUGCACAUAGACACAGCAACGGGAUUGACAUGCCCGGCUACACACAGCAACAUAGACAAGUCGCAUGAUGAAAUCUUGAGUGACAGAAGCCAAAUGCAACAGUACAUACUAGAUGGUUCCAGGUGUAUUACGUUCAGAACCAGACAAAACUAAUUUAUAGUGCACCAAAGUCAAGAUAGUGAUCGCCCUUAGGGUUGGGAGGGGACGAGGGGAGAGCUUCUGGGAGCUGAUCCAGUUCUGUUGUGUAAUCUGGUGCUGGUUCCCUGGGCAUAUGUAUUCUGUGAAAAUCCAUCACAUGACUUAAAUAAAAUGUACAUUACUUAAAUAAAAAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications