v24

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Homo sapiens (human) FNDC1 antisense RNA 1 (FNDC1-AS1) URS000075CD5F_9606

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FNDC1-AS1: FNDC1-AS1 is an immune-related long non-coding RNA (IRlncRNA) that has been found to be upregulated in pancreatic cancer tissues compared to adjacent normal tissues [PMC9676238]. It has been shown to be negatively correlated with MSI scores and MATH scores in pancreatic cancer, suggesting its potential role in predicting pancreatic cancer heterogeneity [PMC9676238]. High expression levels of FNDC1-AS1 have also been positively associated with CA199, tumor size, and tumor stage [PMC9676238]. Furthermore, FNDC1-AS1 has been found to have a high-performance predictive effect on 3-year survival in pancreatic cancer patients [PMC9676238]. In addition to pancreatic cancer, FNDC1-AS1 has also been found to be upregulated in bladder cancer and lung cancer [PMC9676238]. It is suggested that FNDC1-AS1 may serve as an independent prognostic biomarker for pancreatic cancer and could potentially guide individualized treatment and improve prognosis prediction [PMC9676238]. However, the specific mechanism of FNDC1-AS1 needs further study as it has not been extensively reported on before [PMC9676238]. The expression of FNDC1-AS1 is positively correlated with stromal score, immune score, and ESTIMATE score in pancreatic tumor tissues, indicating a lower tumor purity in the high-expression group of IRlncRNAs that includes FNDC1-AS 3[PMC9676238].

Genome locations

Gene Ontology annotations

Sequence

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CCUUUCUUUUCCUUUUUUCCCCGCUGUGCCUGAAUCUCCCGGGACACUUAGACGGCUGGAGCCUCCCGACUCCAAGGCGGGCGACGGCAAAGUUAAACGCCAGCGCGCUGCGGUCCCCGGGCACCGAGGCGUCCCCGCUCCCGCCACCCACACAGGGCGCCAAGUGCCCCGACCCGCGAGUGACGAGGACGCACAGCCUGGAAGCCUCGCGGCCCUCCAGAUGGACUCGGAGCGCCCCUGGAGGCUACAGUGACCUAAGCUCUAGGAAGGCCGGGUCCUGGACGCCGCGUGCUGCUGUCCGCCGCCGACCGGUGUCCUCGCAGAGAUAACCUGGCUGAACUCACCGCCCAGCGCUAUGUCAGUUCUCCCUCAUGACAACCCAAAACUUGACCGGAUUUGUGUUCUGCAGAGAGGAAAAAAAAAAGCGGCCACCGAACACCAGUGCAGUAGCCAGGAUGGGCCUGUGGCUCUGGCUGCAGCCUCCAGGGACACCAGCUGGAGAGAAGGAAGCCACGCAUGGAGAGCGGCCAGGCUCAAAAUAUCUUAAAGAAAAUGGAACUCGGAGUCAGUCAUCUGUUCUCAACGUGGUCAUCUCAAAAAUAUGAGCACACGGAAGUUUUCUUCCUUCUUGUCAGUUUUGAGUCCAAUAUCAAUACUGUUGUCCUGUGAAAGAUUUUAAGAUUUAAAUGUUUUUUCAUGUAAUUUCCUGAUGUCUUGAUUGUUGCUUCUAUUUUGUUCAUCAAAACCAAACAGAGUGGAGGUUGCUCUGGGGCUGGAUGGAUGGCCAGUCAUUAAAAUCAAUGCCUUAUUAGUCUGCCUUAAAAAAAAAAAAAA

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Publications