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Homo sapiens (human) long intergenic non-protein coding RNA 1359 (LINC01359) URS000075C44C_9606

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LINC01359: LINC01359 is a long intergenic non-protein coding RNA (lncRNA) that has been found to be dysregulated in patients with male infertility [PMC9598197]. It has been shown to have interactions with approximately 100 genes, with one target gene being lncRNA GNAS-AS1 [PMC9598197]. In addition, LINC01359 has been found to be upregulated in patients with intervertebral disc degeneration (IDD) [PMC9353269]. It is one of the four key lncRNAs, along with lncRNA GNAS-AS1, lncRNA MIR100HG, and lncRNA LUCAT1, that have been identified as being significantly upregulated or downregulated in the IDD group [PMC9353269]. LINC01359 has also been associated with hepatocellular carcinoma (HCC) [PMC9353269]. Furthermore, LINC01359 has been found to be differentially expressed following GP-C treatment [PMC9961609]. It is part of a subnetwork of genes that are potentially governed jointly by TINCR and LINC01359 and are involved in pathways related to cancer and core histone protein domains [PMC6547626]. Overall, these studies highlight the dysregulation and potential functional roles of LINC01359 in various diseases and biological processes.

Genome locations

Gene Ontology annotations

Sequence

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AAACAGGCUCCAAAAGCUUGUUACUUGCUUGUAGUCAAACAGAAGGCAGAGCUGCGAAUCAAAUCCAGGUUUGUCUCGACAUGCCACUAGCUCAUACUUCCCUUGGAUCAGCCACUAAAUGGCUUUCACUCCAGUGAGCAGCGACCAGCACCAGAAUUAUGGAACAUUUAUCAACAGCCUAAAAUAAAGACAACACGAGGAGAAUUUGGUUGCUUAUAUAGAUUCAAGGUACAAUCCUGCUGGAUUCUGGAAGAAAUAUCACAGUGUGCAUGCACAGAAGUACGACCAUGUGAAGAGGUAGCAAGAGAGCAGCAAUCUACAAGCCAAGGAAAGAGGCCACAGAGGAAACCAACCCUGCCAGCAUCUUGAUCUUGGACUUCCAGCUUCCAGAACUAACCAGGGACCCCACUCCCAUGCCGACAGUAUGGGCUGCUGUCUUCAGGACCAUUGCAAGGCUGCAGGAAGACUUAGAGGCAUCAUCCUGCCUUGGCUUCUGGUUGCCAAGGUGUUCUGCCUGAUACCAACUUUGUCAGCAGUCACCAACUAGCCAUGCUUUUCCCUUGAAGGCACAUGUAGAUUGCCUAACCAUCCACACCAGGCAAACAAUUCUUCAAAUGUCAUGCCCUUUGCACUUCUGUUCAGAUCCAGCCUUAGAGAAGCUUGUGAAGCAAUGACUGUUUUAAUUGGUCUCCUGGGUACCCAGGCCUAAUCCUUUACCAAGUCACUAGUUAUCCCAUGUUCCUUAUCUGUCUGUCUAUCCAUCUAUCCUUCCAUCCUCAUCCAAUACUUACAGAAUGCCUAUGGCUGCAAAUACAAGGAUGACUGCUUGGUUCCUGCUGUCCAUAAACUCACAGCCUGGGAUAAGUGUCCUUCACGGUUCGGUUCACAUUUCACAAGCCCCAUGAAGUCUAUCUGGAUUUUCGAUGGAUGUCUUGCCUUUUCCUCUACACACUACAGGAAGAGUGGCCACCCCUGCCAAGGGCCUAGUAUAGUACCCUAUACAUGUAGCUGAUCAGUUGAUUGUUACUGAUCAUAUGUAUCCUGCAUCAUGUUAUAAAAAAUUAACACAGUGCUUGGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications