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Homo sapiens (human) STARD7 antisense RNA 1 (STARD7-AS1) URS000075C0AB_9606

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STARD7-AS1: STARD7-AS1 is an upregulated long non-coding RNA (lncRNA) that has been implicated in cervical cancer [PMC10125867]. It is part of a 10 autophagy-associated lncRNA signature that can differentiate cervical cancer patients into high and low-risk groups and predict their 5-year survival outcome [PMC10125867]. STARD7-AS1 acts as a sponge for hsa-miR-151a-5p and hsa-miR-151b, leading to the upregulation of three differentially expressed mRNAs [PMC9353269]. The m6A, m5C, and m7G modification sites on STARD7-AS1 have been experimentally validated [PMC9019570]. In high-risk cervical cancer patients, the expression of STARD7-AS1 is upregulated [PMC9019570]. STARD7-AS1 is also associated with proteins involved in lipid transfer and proteolytic activity [PMC5016936]. It shares a motif with other lncRNAs involved in covalent chromatin modification, histone modification, DNA transcription, cell fate commitment, and cellular response to steroid hormone stimulus [PMC8050902]. In ceRNA networks, STARD7-AS1 is co-expressed with other lncRNAs such as EPB41L4A-AS1, SNHG1, CTBP1-AS2, PVT1, MALAT1, MIR22HG, UBOX5-AS1 KRTAP5-AS2 TP73-AS2 LINC00469 LINC00926 LINC00667 [PMC8481885]. In TCGA-BRCA RNA-seq dataset analysis for breast cancer patients' survival prediction model development, the expression of STARD7-AS1 was used as a reference gene for the analysis [PMC6868758]. Cox regression analysis showed that STARD7-AS1 was an independent prognostic indicator for CC patients [PMC8667135]. STARD7-AS1 is one of several autophagy-related lncRNAs that have prognostic value in cervical cancer [PMC9028856].

Genome locations

Gene Ontology annotations

Sequence

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GCAGCCUCCGCGGGAGCAUGCCGCCUCCCGCAGGGCCCGCCGCGAGCUUCCGGGGCCCAAGGAACCAGUCCGGAGGGGCGCAGGCGGUGGUCGCAGCGUCCCCCUAAAUGGCCGGCCACGAACCCGUCUCACGGUCCCGCGGCCAGGAGCCGCCGCUCAUCUGUCUCUGCAGCCACCGCUGAGGAAGAGUCUCCUCUGAGGGGAGAGUCGGUCAUGGCAGCAGACGCCGGGAUGGCUCCGCGACUGCUACACCAGGCACUCCUGGGCCCGGGCAGCAGACCAGUCAGCCCUGUGGCUCCUCGGCGACCUCCAGCGGGCGCCCGGGGCCGGGAUGCAGGGCGCGCGGACAGAAACGAGACAGACAGCUCAGGCCCAGCAGCACGCAAGCUCCCGCGCCUUCCGCGACUGCCACACGCGCGGCGCGCGCGCACCCUACUUUUUCUCCGCCACCUGGGCCGUGAUUGGGCGCGACCUGGGCUCCUGGGUGCUCAUUGGCGCCGUGAAGUGCUCGUCACCGCCCCCUCCUGCCCCUUCAUGCAUGCGCGGAGGCCGCCUGCUAGCAAGGUUCCCACGUAACAUCACAUCAGACCCAAGGGCCCGUUCAUUGCAAGGCGAAGGAGGCAUGACAAUGGCACGUGACCAUGGGAUCACUGGUCCUGUCACAUUCUGCACCACCCAGAAGAUACUGGCUUGAACGAAGAGAAGAAAUGGGCUGUUGAAGGCGUAGCUGAGAUGCCAGCUCAGAGACGAUGAUACCAAGUGCUGAACCUGAGAGCAGCCCCAGUACACUCCCUGCAUGGGAAUCUCCAUCUCAAAGUCAGCCUCCAGGGAGCCCGCCCUGAAACAGAUUCUGUCAUGGAACUCAACAGAGUAUCCUGGUGCGGAUAACCAGUGUUGGGAGUUAGAGCACGGACUCUCUCCACCUGCACGGUGCUGGAGCUCUGCACACCCCCUCUGCAGCCAUCCCUCGCCGCUGUCCCUUAGCUGACGCCCUUGCCCUCUGUGUGUCCUUCCUCAUGGCCUGCAGGUUUCAGAUCCCAAGCUACAGAUCAUGUCUUCUAGUCUGGGCUCUGGCAGAGAGUUCGGAAGCACUCUUAUUAUCUUAGCAGCAGCAUGUGUGGAAAUCAUUUCUCAUUACAGCGGAGGGCAGGCAUUGUGCAGAGGGUUAAGUGGGCCUGCUUGAAGUUGGUUGUUGUUAGCUCUCAUGUCUAUGCCUUGGUCCCUUUCCCCUCAGGACUUGGAGAGCAAGCUGUUUGAGUCUGAUGCAACCCCUGGGCUUUGACUAUCAUGCCAAAAGGCAGCAAAUAAGUGCCUUUUCUUCCCUUCAGAAUACAUGGACAAUCCAAAGCUCUAUUAGUCUAUUAUUCAGAAUGAAAAGUGUUUACAAUAUUCGUCCUCUUACUCCUCAGUAUGUGAGACUGUUCCUCGUAGCAGGUAAUUUCUUCCGAAUUCAAAAACUCCUCAUGGAAGCAUCUGUUUUUGUCAUCAAGGAGGGGGCUGUAUGUGGAAUUGCAAGGCCAAAGACAUCUCGGGUCAACUCUUCUCAGGACCAGAUCCAAGUCGCCAGUGAGAACACACAUUCAGGCAGCCUCCACCAGCGCCCUGCCUCAGGAGCGAGGCUCCCUGCUUCAUGUGGGCAAGAGCUGCCCUUGUUUUCCCAGCGGGCAGUUGGGGGUCUGGAGCCUAGGAAGCAAAGUGAAGCACACACUCCUGCUUCCUUCCUUCCCUGCAGUUGAGACGGGAGUCUUACUUUGUUGCCCAGGCUGGUCUCAAACUCCUGGCUUCAAGCAAUCCUUCCACUUUGGCCUUCCAAAGUGCUGGGAUUACAGGCAUGAGCCACCAUGCCCAGCCUCCUUCUCUUACUAGCUGAGAACUAAGAGAAGACACUCUGGAGACAGAGGAGGAAACAGUGACGAUGCCACAUGAUGAAUACAUAAUGGAGGGUGAAGACAAGGCUCCGUCAGGGGCACCAAGGAGGGAAACCCAGUUCUGUGGGGAAGGUAUGGGGCAGCUUCACAAGCCCAGUGUCUGCUCCCUUUGUGGGAGACGUGUUGUUUCAGCAUCCAUUCCCCCUUCUUUUAGGAAAAGUGCUUGAAUUUCCUUUUCAUGGAACCACCCACCUCCCUCUCAUCCAUGCAUUCUAUUCCCAGUAUCAGGGGUAGACAAGUGACUUCAGGCUUGGCCAAUUAGGGUUCUGACUCUUGGUCAAAUCAGAGUGAAUCCUGAGUCAUUUGUAAACUCCAAGGAAAGGGCUUGCUUUGUUUUCUGUUGAAUGCAGUGCUCUGAGAUAGCCGGAAAUGAAACUGCUCUCUUGCCACACUGAAGGCUAGAGAAGGGCCUGGCCAGGAAAUGAUGCCAGUGAUCAGGGGUGGAGCUGGAAGAGGGGGAGUGAGGAGGCCCAGACAUCUUGGGAGCCCCAAAUUCACCUCAGGAUUUAACUUCUCCGCUGCUCAGCCAAUAAAUUCCUUUCUUCCAUGACUAAAA

Taxonomic tree

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Publications