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Homo sapiens (human) spermatogenesis associated 42 (SPATA42) URS000075BBB0_9606

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SPATA42: SPATA42 is a specific extracellular vesicle lncRNA that has been identified as a potential marker for predicting the presence of sperm in the testis [PMC9436424]. It is one of the nine lncRNAs used in a prediction model that demonstrated high sensitivity (88.9%) and specificity (100%) in predicting the probability of sperm retrieval (SSR) [PMC8658396]. The dysregulation of SPATA42 has been observed in patients with male infertility, suggesting its potential role as a diagnostic marker [PMC9598197]. Additionally, SPATA42 was found to be down-regulated in patients with male infertility, along with other lncRNAs such as NSNK1G2-AS1, LINC00467, and ZNF295-AS1 [PMC9436424]. The dysregulation of SPATA42 was also observed in multiple studies and different sub-types of male infertility [PMC9598197]. Furthermore, SPATA42 was included in a prediction model along with other differentially expressed testis-specific lncRNAs to predict SSR probability [PMC10116801]. In another study, SPATA42 was identified as one of nine lncRNAs associated with male infertility [PMC8491582]. Overall, these findings highlight the potential importance of SPATA42 as a diagnostic marker for male infertility and its role in predicting SSR probability.

Genome locations

Gene Ontology annotations

Sequence

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CAGGCUGUGAAAACACUUCAGGCCAGUCCCUGAGUAGGAAUGGACAACAAGGUGGUCACCAUGCUGACAGCUAUUCCCUGUGUGAUUUACUUUAUUAUGAAGUCUAAAUUUGAUGCUGAAGUGCUAGCCUAAGCUCACUAACCUGCCAACUUAGAGAAGAAGGUAACCAUGGCUAGGAUGACUGGGAAUCUGAUGGACUCAAUUAAGAAUUUCUACAGAUGGGAAAACCAAAACUCCUUAGUGGCAAGAGGCCAAAGAUGGUCAGCGAAUUGUUGUUUCCGGCUGUUGGAAGUUGACUGCAGUUGAAUAACAGAACAAAAACGGAGCUUCAAAAUCAUGGCGUGCCUGCUUCUUCUGGGUUCUUUUAACUGCAAGCAAUCAGCUUUGAAGAGCACCUCAAGAAUAACAUUUACAUAUGAAAGAAAAUAGGAGAUGGCUCAGAAUAAUAUGUCCAAGGCCACGCCCAGGCGUCAGGGAUUCAUGAAUUUUGUAUACAGUGUAUGAUGUUUCUAGAUUAAAAUAUUUUCAAAGGUAAAAAAAAAAAAA

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Publications