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RNU5A-1: RNU5A-1 is a non-coding RNA gene that has been mentioned multiple times in the provided text [PMC5568388] [PMC6467950] [PMC7272712] [PMC9467413] [PMC9803687] [PMC9194484] [PMC7610016] [PMC5587755] [PMC5137419]. It is not a small nucleolar RNA (snoRNA) and its involvement in various cellular processes is not mentioned in the provided context. In the low IA ancestry group, RNU5A-1 was identified as one of the unique genes [PMC5568388]. It was found to be differentially expressed between R. conorii and R. montanensis-infected cells [PMC6467950]. In a network analysis, RNU5A-1 was identified as one of the splicing factors associated with survival-associated alternative splicing events [PMC7272712]. In another study, RNU5A-1 was excluded from the training cohort but found to be associated with alternative splicing in patient outcomes of endometrial cancer and colon cancer [PMC9467413] [PMC9803687]. Additionally, RNU5A-1 was found to be downregulated in G1 and G2 samples compared to control samples [PMC9194484]. The gene also plays a role in snRNA processing and has been studied in relation to INTS11 depletion [PMC7610016] [PMC5587755]. The binding of rp eS1 protein to RNAs transcribed from the RNU5A-1 gene has been observed, suggesting its involvement in splicing processes with U11 snRNP and U5 snRNP [PMC5587755]. The accumulation of extended forms of U4atac (RNU4atac) and U5 (RNU5A-1) snRNAs has also been observed under certain conditions [PMC5137419].
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