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hsa-mir-718: Hsa-mir-718 is a stably expressed normalizer that was identified using NormFinder on RNA-seq data [PMC7329382]. In addition to hsa-mir-718, hsa-piR-31068, a highly expressed piRNA, was also identified as a stably expressed normalizer [PMC7329382]. TaqMan probes were used for various genes, including hsa-mir-718 [PMC5591958]. The study also identified 16 markers, including hsa-mir-718, using specific probes [PMC4076980]. In patients with AS (ankylosing spondylitis), six miRNAs were found to be overexpressed (hsa-miR-193a-3p, hsa-miR-29b-1-5p, hsa-miR-505-5p, hsa-miR-194-5p, hsa-miR99b3p and hasmiR200b3p), while 14 miRNAs were downregulated (hsa-miR36633p, hasmiR513a5p hasmiR146b5p hasmiRNA1972 hasmir718 hasmiRNA3138 hasmir215p hasmir630 hasmir575 hasmir301a3p and so on) [PMC4989063]. However, it was found that hsa-mir718 was not amplified by real-time qPCR due to its low abundance in the plasma samples analyzed in the study [PMC6114494].
References:
[PMC7329382] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329382/
[PMC5591958] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591958/
[PMC4076980] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076980/
[PMC4989063] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989063/
[PMC6114494] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114494/
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