v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) long intergenic non-protein coding RNA 941 (LINC00941) URS000075A607_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

LINC00941: LINC00941 is a long non-coding RNA (lncRNA) that has been implicated in various cellular processes and diseases [PMC7521336]. Activation of the WNT signaling pathway by ligand stimulation has been shown to restore the impaired growth of oral squamous cell carcinoma (OSCC) cells caused by LINC00941 suppression [PMC7521336]. LINC00941 has been found to interact with ANXA2, and their binding requires specific nucleotides in LINC00941 and the Annexin 1 domain [PMC9385862]. Deleting EP300 did not affect the promoter or expression of LINC00941 in HOK cells [PMC7521336]. In colorectal cancer (CRC), LINC00941 promotes metastasis by preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway [PMC9424287]. The expression level of LINC00941 has been measured in laryngocarcinoma cells using RT-qPCR [PMC9280015]. Knockdown of LINC00941 attenuated the binding effect between ILF2 and YBX1, highlighting the importance of LINC00941 in their interaction [PMC9886991]. Knockdown of LINC00941 resulted in aberrant expression of numerous genes, as shown by transcriptome sequencing analysis [PMC9818929]. In pancreatic cancer, high levels of LINC00941 expression were associated with increased MAPK activity and progression [PMC9818929].

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
GGGGACGUGGCUGAAGUCAGUCGGGCCGCCCGCUUGCUGCACGGCAGCCGUGGGACUGGCACAGGCUCCUCGGCAGCAUUAUGGGCAGCUGGUAGAGCGGCCACUUCUGAGAGCCGGAUGGGCCUUCCGAGGUCGGGCCGUGCCCCGCUGGGCAGCGCAGAGGGGGUGUGUAGGGCACGCGACUUGGAGCCAGGUCCAGACCCAUCCUGGCUCCUCUCAGGGCUCCUUCCCCUGCCCCCAUUCCACCCCAGCCCUGCUGGCUGUCCCGCAGGACCCAGCGCCGCGGUAGCCUUCUCUGAACUGCGGCUCAGGCGGAGGUGUCACUCCUGCCUCCAGCCCAGGAGGGCAGGUCAGGUUAUGCAACGCGUGCCGCGCGAUCUCCCCCCACCUCCAACCCCCUUUUCUCCCGGGUCCACACCGCAGUUCCCACCGCUCCGGGUGUCCUCCCCAGUGCGCCGCGAUUUUUGUGUCCAAGCCCCAGAGUCCCUCUGAGACCAACCCCCAGCCAGCACAGACUUCCUGCCUUCCCAGCUCGGGGAUGUGGUCUCAUUAGGUUGCCCAAGCUGGACUUGUACUCUUGGCCUCAAGAGGUCCUUCCAUCUCAGUCUCCCAAGUAGCUGGGACUACAAGCAUGCACCACUACACUCAGCCAAAUACUUUCAAUAAUUUGCCAGCUGACAACUUGAUUGGGUUCUCCUUCAGGUUUGAAGCGCCCUCGAGAAGUGUCUAAAGGAGACAGUUGAUAGCCAAACAACAGUUUUGGAUUCACUGACUGAUUAUGAAAGAAGCAGUAGACUGGUAUCAAGAAUCAGUCAGCAAGGAGGCCCUCACCAGACGCCAGUGCCAUGUUCUUGGACUUCUCAGCCUCCAUAUUCAUGAACUAAGUUUUUGGAAUCCUUAGGCUUCCACGUGUGGAAAGCCUGAGCUAACCUACUGGAGGAUGAGCCAUCACCUGGAGCAGAUUCAGGCCAUCCUAGUUGAAGCCUCCCUAGGCCAAGCAACCGUCCAACUACCAGACAUUGACCAUUCAGCCUUGAACAUUCAGCACAAAGACAAAACAGACCAGACCAGAAGAGUCCCACAGAAUAGGGGAAACUAUUCAGAGAAAACUUAAGCCACUAAGUUUUAUGGUGUUUUGUUCUGUAGCAGAAGCAUAGGCAUACUGACAAUACAAACCGAAAUCCUUCUAACGUAGUGGACCUUUUCAGGCCAGCAUUUUUUCCUUGAAAACCUGGAGCAUGUAUCCAUCUUAUAGCAGAGAUCACUUUCACAAUGUUUGGGCUCUUGAUUUGAAUUGAUGAUGUAAUGAGCCCUCUAUCCAGAUUGUAACUAAUUACUCUGCGAAUUGACUGGAUUCCACACCCUUCUAAUAUUUUACUUUUCCUCUUUUAUCAACUCUCAUUCUUGCUGCCAUGAUCAAUGGACCAACUAUGCUUAUAACCACAAAUUUUGAUAUGCUUAAACAAAUGAACAAAUAUAUUUAAUAAUUUCUUUUUUUUUUUUGAAAUAGUAUCUUGCUCUGUCACCCAGGCUGCAGUGCAGCAGCGUGAUCUCAGCUCACUAUAACCUCCACCUCCCGGGUUCAAGUGAUUCUCCUGCCUCAGCCUCCCAAGUAGCUGGGACUACAGGCGCCCACCACCAUACCUGGCUAAUUUUUUGUAUUUUUAGUAGAGACAGGGUUUAUCCAUGUUGGCCAGGCUGGUCUCAAACUCCUGACCUCAAGUGAUCCUCCUGCCUCGGCCUCCCAAAGUGCUGGGAUUACAGGUGUGAGCCACCAUGCCCAGCCAAUAAUUUCCUGAUAUAAUAAAAAUGCCAAUACUAUACAAUUAAAUAGUAAAGUGAUAAAAAAUAGGAUAACAUGAUAACCACUAAUUAAUAUAUACUACAUAAUCAUC

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications