mir4301: MIR4301 is a non-coding RNA, specifically a microRNA, that is 65 base pairs in length and is located on chromosome 11 within the intronic region of the DRD2 gene [PMC3772989]. This microRNA has been identified as having a significant association with systolic blood pressure (SBP) regulation in sickle cell disease (SCD) cohorts, as indicated by gene-based tests and the presence of shared associated SNPs with the DRD2 gene [PMC3772989]. The expression of MIR4301 is tissue-selective, and it has been found to have a significant p-value ranking in studies examining physically close genes [PMC6836538]. Notably, MIR4301 has a predicted binding site on the 3’ UTR region of the DRD2 transcript, suggesting that it may play a role in regulating DRD2 expression [PMC3772989]. The significance of MIR4301 was underscored by its p-value of 5.2x10^-5 in genetic association studies [PMC3772989]. Additionally, MIR4301 is one of several microRNAs located within the 11q23.3 SRO region; however, its function and that of other miRNAs on chromosome 11q remains to be fully elucidated [PMC5492892].