v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) RAB6C antisense RNA 1 (RAB6C-AS1) URS0000759F3A_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

RAB6C-AS1: RAB6C-AS1 is a long non-protein coding RNA that has been implicated in various cancers, including gastric, breast, prostate, pancreatic, and brain tumors [PMC7087479]. It has been shown to be frequently overexpressed in gastric and breast cancer [PMC7087479]. In breast cancer cells, RAB6C-AS1 has been found to be significantly upregulated compared to healthy cells [PMC8850887]. Additionally, RAB6C-AS1 has been associated with resistance to certain drugs like tamoxifen in tumor cells [PMC8850887]. It is suggested that low expression of RAB6C-AS1 may lead to better outcomes for patients undergoing endocrine therapy with tamoxifen [PMC8850887]. RAB6C-AS1 is considered a potential factor in the development of various cancers due to its association with the RAB6C gene, which codes for a centrosomal protein involved in cell division [PMC8850887]. Furthermore, RAB6C-AS1 has been reported as an inhibitor of proliferation, invasion, and metastasis and acts as a tumor suppressor similar to p53 [PMC8850887]. The prognostic role of RAB6C-AS1 as a potential biomarker for breast cancer has also been investigated. While it was found that RAB6C-AS1 expression is higher in breast cancer compared to healthy control tissues [PMC8850887], it was observed that only CBR3-AS1 had a high chance of being a breast cancer biomarker via ROC analysis [PMC8850887]. Overall, the role of RAB6C-AS1 in various cancers and its potential as a prognostic marker warrants further investigation.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
AACAUCACUUCCUCUUUCUGUUCUGACAUCAUCAAUCCACUUUGUAGUUUGCUGGAAUGAGUUAACAUUUGUGAUAUCGUAAACUACUACAGCUGCAGCAGAAUCACGGAUGUACCUGGGAAUGAGGCUACGGAGACGUUCCUGACCCGCCGUAUCCCACAGCCGAAGCCCGAUUGUUCCAUCCUCCAAGAACACCAGCUUGAAUUUCCUCAGCGGAUUCCCGAAGUCUCCGCCCGCGGACAUGGUGGAACUAGAGGAGCUGUCGCCGCCUCAGCCCAGAGACCUCCCGGACCGAUGCUCCUCCAGCCGGCUGACGAAAAAGGAAAUAGCAAUGUUUUUUGAGUAUGGCAAGUGUUUCCAAGCAUUCAGAAGUGGAGAGUGUAGGAUAUCCACUGCAAAAUGAGGUCUGCUUGUCAUCCUCUUAGUCUCCACUGCUAUCCCUCCCUCAUCUCUCUCUGUUUCAUUGAGACCAAAAGACUAGGAGCCUGGCUUCUAGUUUUCAAAAGAGCUAAGUGACUGACCUAGGCUGAUGACUCGCAAUCCUCGUUUUACAGUUGAACCACCUGAGGAGCUUUUUCAAAAUACACAUGUCUGGUUUCCAGACCCAGAGAUUCUGAUUGGAUGAGAAAACUGAUUUGGAGAGAUACUGAGUGAUUUGCCCAGGUCACAGCUGGCAUAAAGGCAACACAAGUGGUCAGGCUCAGCUACUCUGGUUCCUACAGACUUUCCCCUUUGGGAUAGCGUCUCUCACCAUCUUGACUGCUUACCAACAGAAGCGCCAAAACCAAACUUGAGGAUGUCCACAAGCUUGCUCUACACUUCUACAUUCAUCCUCAUCUUUUUUGUGUGUGUUUGUGGGGUAGGGGAGGUGCAGUGUUUACUCAGUGAUCUUUCUACUUUCUAGAAAGUGUCUGUCCUUCAAAACUAUUUAAGAGCCUCUCAUUAGUCAUUUUUUCUCUUAUAUGCUCUGGUUGAGCUUGAAUAGACCAGUUGUUGCUUAAGAAAGAAACUGAAAAGAUUUUAGCUUUUCAGUCCUAUUUGGCAGAGGACUUCAGCUACCUUCUUAUGGUCUUUGGCUGUGUUGGUGCCCUCAUGUGCUCUGGGCUAAGCCACAUACUAAAUUGACUUUUUGGUUUGUAUACCCUUGCUCUCGCCUUCUGAUGAAAACACCUUACCCUCACCACCACCAUCUUUGCUCUCCUUUCCCAAAACUCUUUCCGCCUUGCUGCACUAAGAUAGUGACACCUCCACCACACGUCAAUUCCACACACAUUUAUUAGGUACCUGUGAAGCAGGAUCUUAUCCUCUUAAACUUCCACUUCUCACACUAGAGAGAAAGAUAAGGAAGAUGAGCAAGUGCCUGGAAUGGGGCAGGCUGAGUGGUCACACAGGCACAGAGGCACACUGAGAACCUACAGGGGAGACUGCAGAGUGCCUUCCCUGAUGCUGCAGCUGGAAGUCAUCCUUCCCUCCACCUGGCCCCUGAGACACUCUACUCUGUAGUGUGCAGUCUGAUGGCACUGCUAGAUUUCUUUUUCAGCUCAGGGCCACAGCUUAAACAGCUUUACCUUUCCCCUCAGCACCUGUCCCACUACCUUGCACACAGGUACUCUAUCCGUGUUUAUUGAACAAAGGAGGGAAACUGAUUUCACUUUCACUUGUUCAUUAUCAUUCCAAUUUUUAUGUGAAAAUGGCACAACCCAUUUGGGGUACACUCAUCUCAAAAGAAAAGCCCAAGACUACCUCUGACUGGUACCACCUUUUUUGUGGGUUCCUUGGUGAGAAACCUUUAUCUUUUUCAUACUUUUCUAUUCUCCAUCACUUCUCCAAAAGUGUCUCUUUCCAGCUCUGAUUUAUUCAAAACACACAAACAUUCCUGUUUAGAGAUUCUAGCCCAUGGAUUAUCCGGCUAGUUAGUACCUCUCCUGUUCACUUGGUUAUACUUUAUUAUUGCUCAGAGGUUGGGGAGGCAGAAUGACUGUGUCCCCUCACCCUGGCAGAAUGACUGUGUCACCACUAGGAGCCAUUAGGGCUUCUUCCCAGGAGGACUGCCUGCUUGCUUUCUGGGGACUAGCCCUUAUUUCCCUUCUGUGGUCCAGUGGGGCAAGUGAUUUGUAUUAGACAAAUAUUUAUAAGAAACAACCCCCUCCCCAAAAUAGAGCCACCAAGUAAAGCACAAGCCUGAAAGAUGAUGAACUAUGAAUUGUCUCUAGUGGAUAUAAAUUUCUGCAAAUAUAUCUCAGUCUUUCUCUCUUUUCUCUGGUGAUUAAAAAGUUGGUUUUUGGUAAGGAAAAGGAUUUUUGACCAUAGAGUUAUGCAUCAUGGAAAUUCAAACCCGAUUUCUUAAUACCUGGUCUUCUCCGAAGAGAAAUAAUGAUAGUAAUAGUGGUGCUGGGAACAAUAUGGAAGAUUAUUGAAUGAAAUGGAUUAACUUGAAUAAAAUGCUGUGAAUUAUCUCUAAAAAAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications