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Homo sapiens (human) CADM3 antisense RNA 1 (CADM3-AS1) URS0000759D0A_9606

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CADM3-AS1: CADM3-AS1 is a long non-coding RNA (lncRNA) that has been found to be significantly down-regulated in both colorectal cancer and cervical squamous cell carcinoma (CESC) [PMC8798118] [PMC9936453]. In contrast, high CADM3-AS1 expression has been associated with a more favorable prognosis in cancer patients [PMC7100599]. The genomic region harboring CADM3-AS1 has also been found to be significantly more amplified in patients with low CADM3-AS1 expression [PMC7100599]. In lung cancer, CADM3-AS1 has been identified as a potential therapeutic target and is downregulated in tumor tissues [PMC9887198]. In a study of LUAD patients, CADM3-AS1 was included in a prognostic signature along with other lncRNAs that were found to be relevant to patient prognosis [PMC9887198]. Furthermore, low expression of CADM3-AS1 has been correlated with poor overall survival (OS) in CESC patients [PMC9936453]. The downregulation of CADM3-AS1 has also been observed in Hela cell lines and is associated with worse prognosis for CESC patients [PMC9936453]. Overall, the dysregulation of CADM3-AS1 expression appears to play a role in the development and progression of various cancers, making it a potential therapeutic target and prognostic indicator for these diseases.

Genome locations

Gene Ontology annotations

Sequence

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GGCACUGACUCCAUGGCUCAGAGGAGGGAAAUCCAGGGAAGGGCUGAAUGCUCUGUGUUUAAGGGAGAGAUAGAAUGGACAGCUGGGCAAACACACACCCGGGGACUCCUUUCUCCAAGACCGAUGGGCAUUGGGGGUGGCAGAGGAAAUACCAGCAUGGAACAACAUCCCAGGGACCCGCGUCCUCCCCAGGUUACAGUCCUGGGUCCCUGCAUGGCUGCAUGUUGUCUGCAGGCCACAUCUCCUCAGGACUCCCGCACUCAUCACUUUCCCAUUGCUAUGGAAGAGAGGUGUCAAGGUGGCACCUGCCUCCCUGUCCGUAGUGCUCAGGUGUGUGGCUACCAGAGGAAAAGCCACUCCCAACCUUUGCCGACAACCAUCCCGUUUCUGGGUUCCUGGAGAAGUCUGGGAAGCUGCUCUGUUGUAGAGGCUGAAAGGAGGGCUGGUGAGAGCCCCCAGCUGAAACCAGCCCUGCCCCUUACCCUUCCUCACCCCUCUACCUUCACUCUCCUCCUAACACUCCAGGGUUUUGUUUUUUGUUUGUUUUUUGCUUUUCUCACCCCAGGGCUCCUGCCUCUCCAGCCUGGAGACAGAUUUGAUUUGGGAUUGUUACAAAAAUAAUAAUAACCCAAAUGCAGAGAAGCCACGGAAAGGGCUGAGGGCAACCCUCCCCUCCCCCCGCCCUCCUCCCUCCCCAUUCCAAACCGAGUACAAAACCGCACCCAAAGCAGACAUUCUGUACAGGGGGGUGGGUGGGCUGGGGAGCAAGCGGGAGGGGCGGCCCUGCGGUUGCUCUGUACAAGUCCGGGUUGGUGACGGCCCCAGCAGUCCCCACAGGGCCCCUGGGGGGCGCAGGAAGUGGGCAGGCGCCUCUAGAUGAAAUAUUCCUUCUUGUCGUCCCCUCCUGACUGCCCGCCUUCUGCAUUGAUGAUGGCCGUGUCCGCGUCUGGAGCAUCGUCGGAGCCUUUUGCCUCAUGUGUCAGUAGUGGCCAAGGAAGAUGAGCAUGAUGAGCAGCAGGAAGACAAUGAAAGCCACGAUCCCACCGAUGAUGGCGUGUCCCGCCCACUUAAGGAUAUUCCUGGAAGAAGAUGCAGUAGCUCCUUCUACCACCAGGCGUCAGCACUGGAAACAGACGCAGUCCAACAGGACUCCCUCUGCCUGGCUGUUGAGCACAAAGCAGAGGGGAGAUCAGCAAGAUACCAACCACAAGGGCACAAGAACUUUCUCUCACUGCCAAUCAUCAUCAGAUUGGUCUGGAGAGAUCUGGGGGCAGAGACCGGAGCUCAGUGCAUUGUCCUUGCUCUUGGCAUCCUACAAUAGCCUUGUUGUGCUGAGGCAGCUCCCACAUGCUGAGGUCUGCCCCUGGAGUGGGAAUCACCCAUCCAGACAUUCUGAUCCCAAGAACUCAGACCUCUUAUCGCUGGGAGGCCUGGCUCUUAUCCCCUCAACUGUUUUAAUGAGUGUCUCAAGUAAGGGAGCCUCUGAUGUUUCCCCGACAAUGCAUUUCCCCUAUUCUGAGAAAAGAUAAGACUUUCUGGCGGGACCCACAGCCAUUGGGAUCUUCAAAAAAAUCGCCCGUCAACUCUCCAUAAAGGGGCCUCUGUGUCACCCUGUCACUACUCCUGAAGCUGGGUUUUGUGGUCACAGCUUUGAGAAGAACUUCAGAGAAGGAGCAUCACCUGGUCCUUCUAGAAGAUAUGGCAUCUGAGAAAAGAUUCUGUCUCUUGGCAUAGUACAAGCUUCUCUCUAUUUUCUGUCCAGACCCAGUACACUGUGCUUAAGGUGGGCAGAAAAAAAAAUGACAGCAGUUGCAUGCACCCAAUACCUAGUCUUAGGAGAAGCAACUCUGAGAAGAGCCAGUUAGAGAAGGAAAUGCACCUGCGCCUGCACUUGAGAGGCUUUGGGGCCUCUGCACACAGAAUUAUUGUUCUUGUUGUCAGACAAGUGCAGGGGAUGGAAGAUGGUGUCACCCAGGCCACCACUACCAAAGAAAGGCAGAUGAGAGCCCACCCUUCUAAUGUUUUUUCACUAAGCGGCCAUUACACAUUCUAGAGUGGACCUGGGACCUAAGCCCUCAGGGACCCCAGUGGUGGGCUGGUUUUCCUUUACUCCACUCCCCGUCACAGUUUGGGGAUGUUAUCAGGAAGCAUUUUAAAAAAGGGAAUAAGAUGGACAGAGAAAGGAGAUUCUGGAGGAAGAGAACUGAGGAGGGCUUACCAUUAACAUUGAGGGUGUAGUAGGCCUUGUAGCUGCCCAUGUUGCUGGUGGCUGUGCAGCCGUAGGUGCCACUGUCACUCUUGUUGAGGAAAGGGAAGAUCAGGGCACUCUCCUGGGUCAUCUUCAGGGGUGGCACACUGCCCUCCUUCUCCCAUAGGUACUGCUGGGGGCUGUCGAGGCAGACAAAUCAGAAGAGCUCAGGAGAGCAUAGGCCAGGGAGCUAAAAGAAAAAAAAAAAUAACUGGGAGCAGGGAUGUCAAGGACUGUUUGAUGAGGCUGGAGAAAUUAUCGGGGCCAGAGACACUGGAGCUGCUAUACGCCAGGUGGCCUCUUGGGGUUCGUUCUGGGGAAGCUGUAGAUCUCCAGACUUGUAUCUUACUUUAACUUGGCCUUUGUGGGAAACUCAGGGACUGAGUUAGGGAGUGGCCCCUUCCCAUUUGUGCUGCUUUGCAGAAGAACUAAUUGCAGGCGGACAUUAUUGGACAGUCAGGGAAAUGAGAGGCUCAGGUCAGACAAUACAGAGGAGAUAGGAAGGAGCUGUUAUGUGAAGAAGGCAAUCUGAGAAUGUGGAGAGUAAGGAGGAGACCAGGAAAUGGAUCUUCUUACACUGGAUUGCCGCGACCCUCACAGUGUAGCAACAGCUUCUGGCCCUCACGAGGAUGGGGAGGGUCUGGCCUAAUCAUCGCAGUUGGUGUGUCUGUGGAGAAGGAAAUGGUAUCAAUGAAUACCUCCCCACACGGCUUAGGAGAUUCCCUCACUUAGUUGCACACUACAGCUUCUACCUCUAAAUGUUUCCGCAGCUCAAGAAGUGCAACAAAGACCUUCCUUCUCCUACUUCUCAUGAACAAGGACCAUUAUUGCUAUUGAAUAUGUGAGCAACUUCUCUUGCAACCUUGUGUGAUAGGAUUCUGGAAGGUCUGUCCUUGGUGGGCCCUAAGAGAUGUCUUAACAGAAAGCUGAGAAGGGAAAUGAGUGGUUUACCUGUGCCUAGCAAACCUCCUAGCACAUAGGAAAGACCUAAUACAUAUUUUUUACAGAACAAAUAAAGUUGAACUUGUCACAUAUUGAGCUCACAA

Taxonomic tree

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