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Homo sapiens (human) EMX2 opposite strand/antisense RNA (EMX2OS) URS000073968D_9606

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EMX2OS: EMX2OS is an eRNA that has been identified as a hub eRNA in Kaplan-Meier analysis and correlation analysis [PMC8519253]. It is an antisense transcript that positively regulates the expression of its respective sense transcript [PMC3180702]. The luciferase activity of EMX2OS is suppressed by the overexpression of miR-653-5p, and this suppression is enhanced in the presence of miR-653-5p knockdown [PMC10105521]. EMX2OS is one of several lncRNAs that have been identified, including 21A, Air, ANRIL, Alpha 280, BACE1AS, Dio3os, E2F4 antisense, EvF1 and EVF2, GAS5, H19, HOXA6as, Jpx, Kcnq1ot1, lincRNA-RoR, mascRNA and others [PMC7564176]. Low expression levels of EMX2OS are associated with worse recurrence-free survival in patients [PMC6303026]. The levels of EMX2OS can be quantified using the SYBR-Green-quantitative real-time PCR Master Mix kit [PMC7102881]. Highly expressed EMX2OS has been found to be a protective factor for poor overall survival in patients [PMC8457683]. Overexpression of EMX2OS leads to downregulation of cell proliferation and migration in DU145 and PC3 cells [PMC7398891]. In several melanoma cell lines compared with PM cells there was a downregulation observed for EMX2OS expression [PMC8376646].

Genome locations

Gene Ontology annotations

Sequence

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GUGCUUGGCUACAGCCGCUGCUGCCUCUCGCGAACUGGGCUCCGGGGCUCCCGGCUCCCGAGAACUAGAAGAGAAACGCGAGCGAAGGGAUCGAAACCCGGGGGGUUACCGACUUGCAGACACCGCCAGGACAGUCUGUAACGCAGGAAGAUCCCAGCGGCUCCGGGUCUGGUGAGGGGACCAUAAGCAUGACUGAUAGCGAAUGAGGAAGGGCAGCCCUAAACUUUUCAAGCAAAGCCUCAGAGUUUUGGGUUCACUCAUUAGCAUAGGAAAUCGAUUCACCGAAAACCCAAACAAAGAAAAACAAGCCGACAGUCCAGGCAGGAUGCAGGCAAAUCCAGUUCGGGAUUAAGGGUAAAAGGCUUUUUGGGUUUUUUUUCCUUUGGUUUGAUUUUUUAAAAUAUGGGGAGGGGGGUGACAUCUACCCGAUUCUAGGCUCCGGCAGGAACGCAAUGGGUUAAUGAAUGGACAAGCCGCGGAGUAUUGAUCGGCUGCCGCCGGAGAAAGAAAGAAAAACAAAAACCAGACCGAACCUGCCUUCCCGCUGUGGCUGCUCGGCGCCCCAAUUAAGCAGGGUCAUCUCAGGCUGGCUGCAUGCCUCAGCUGAAGAUCCCAGCUCCUGUCAAUGCCACCUCUCUGCUUGACUGUCUCCUUCCAGAUUCGAGCAGGUAUGAGCUGGGAAGAAUGAAGGCAGGGCAUGCCCGUGUGCCAGCUCUGCACAGCUGGAUAGCUGAGGAAAGAUGUGGAGGAGAAGCCGGGGAUUGUGUGGAAGUCUAAGGGUGUUGUUUGCCCUUUGGGUUCCAGAAGAUGCAUGCCAGGACCCUGGGUGGCACUGCCAGGAAGCAACAGAGAGGAGAUAAAACUCACAGCAGACAGACUUGCCUUAACAACAACUCCCUUGAAUUAAAACACGCUUUUCAAGAAAACAAAUUAUCAGUUCGAUCAGCAAACAGCAGAGAAGUUUCUCUCAUAAUGGCAAAGAAGGGCCGGGUUGCUGACCAGUGAAAGAGCUUCAGAAAAGGAGAGGGGAGAUGAGAUGGCCAGAAGGAGCAAGAGCACCGUACAUCCCUGGACAACCUCAUUCUAAUGGGUCAGGGGCUGGGACGUGCAUUUUGGAGUGCAGGAGAAGUGGCAACUCACAAAUGCUAGAUUUUCUUCUAGAGAUGACCAAGCUGUAGUUCUUAAAGCAGUGGCACUAGGGCAGAAAACUCUCACACUUUGAUGUGCACACACAGCCCCUGGGGAUCUUGUUGACAUGUAGAUUCUGAUUCCGUAAGUCGGGCUGAGAUUCUGCAUUUCCAACAAGCUCCUAGAUGAGGUCCAUUUUGCUGGUCCAUGAAACACACUUAGAAUAAGUAGCAAGGUAUAGGAGGAUACUGACUUUGCUCAGUGAUGCUUGGGCUUCCGUCCAAACUAAAAUAAAACAAAAGCAGACAUAAAUGGCCCAAUUCAACAGCCUGAGAAGUUUGGUGAUAAUGACCCAAGCCCUGGCCUGGUGACCAAGUGGCUGCUCAGAGAGCUCUAUCUCCAAACUCCUUCCCUUCCUGCCUCCCCUCCAAGAGUGAGUAAUGUGCCAGAGUUCAUUGGGGUCUGCUGUCCCCAGGGAAAGGUGGCCCAGUUGCCAAGUGCAAGUGUAUAGAACGGCUUACCUGUGCAAAGCUAUCAGCCCUGGACCUAUGGGCCUAGAAACAUUACUUGCCACUCACUCACUCACUAUCAUUCAUUCAUUUCUGCAACAAACACUUCCUGAGCAUAUGCUAUACACCAGGCCCUGAGCUCAGCUCUGGGGAUACAGGAUGAAUGGCAGAUUGUGCCAUCAGGAAGCCGACUGCACAGUCAGCCCGCUGGAGCACAUAUGAAAAACAAUACGGAUGUUUUGAUUUAUUAUCAUAUUGAUCAUUAUGAUGGUAGCGUAUACUUUUGGAAGGCUUGCCAUACAUUAGGCAUUGUGCUAAGCACAUUAUAUGGUUAAUCUCAUCAAUCUUCACAACCUAUGUGGCAGGUACUAUUAUUAAACCCACUUCAAAGAGGAGGGAACUGAACCUCAGAGAGGGUAAGUGACUUGCACAAGGACACAAGCUAGUGAGGAGAGGAACUGAGAGGAAUGGCCAGACAGGCCAUCAGCCUCUGUCCCCACAUGCUGGGUCUGAGUGUCUGACGGUGGACACAUUCCCUUCCUGGAGGGAGAGCUCCUAGGGAGCUGAUGGCAGCACUGAGUCUGGAAUGUGAUGGGAGUGCAUUAGAUGACGUGGGUGAUCUGAUGAGUACAGAGGCGUCACACUGCAAUGACUUCAUGCACAUAUCUCCCCUUGAAUGCACAGAGAUUCAGCAGAGGCCAGGAGCUCAAGUUUCUGGCCCAGUGUCCCCCUCUUCCCCUGGGGAAAGCCAGGGACACACUGCCUGGCUUUGCUACACCUUUCUAGGCAAAGGCAGUAUGCUCUCCCUCUCCUUGGCCUCCCUGGCUGUCCACACAUCCACACCCACUCACACACACAUGCACAUGAUCAUACACAUUACACAAGCCCACAUGCCCACAGACAUGCUCACACUCACACUCACAUGCAUACACUGCCAUACACAACACACAUACAUACAUUCACACACACUUGCACACACACACACACACACAGUUCUGAUGGCCAAUCUUUUGGGGCUAUGUUGACACUGUGAAGCAGGUGAAACAAAGUCUUUGCCACUCCCUGCUUUGGGCCUAUUAUGUUUGUUUUAUAGUUUAACUCUCAAAAGACAACUUUAUUUUCCAAAAUUAUUCAGGUUCCCAGCCAGGUGCAGUGGCUCACACCUGUAAUCCCAGUACUUUGGGAGGCCAAGGCGGGCAGAUCACCUGAGGUCAGGAGUUUGAGACCAGCUUGGCCAACAUGGUGAAACCCAGUCUCUACUAAAAAUACAAAAAUUAGCCAGACAUGGUGGCACACACAUGUAAUCCCAGCUAUUCGGGAGGCUGAGGCAGGAGAAUCGCUUGAACCCGGGAGGCGGAGGUUGCAGUGGGCCAAGAUCGUGCCACUGCACUCCAGCCUGGGCAACAGAGCAAGACUCCAUCUCAAAAAACAAAAACAAAAUCAUUCAGGUUCUGUAGGGGACCCUCACUGUGUCCUGGAUUCCAUUCCACUUUUAAAGUCCCAAACAGCUUGUAUGGCCACUUCCCUUGACACCCAAACCAGAUAGGAGUCUUAAAUGACACAGAGUAUUGAUGGUUUCUUUAAAAGGAAAUCCACUCUCAAUGGGAAGCUGGAUAACUUCGCAUCCAGAUUUCAUCCAUCUUGGGCUUUGGUGGCUGCUGUUUGUUUUUGUGCAGGAGAAUCUCUCCCAGCCAACGUCGAUUUCACUAACACAGUGGUUAACCUUUGCUCUCUACUCCUGCAUCAAUCUUCCGCCUACCGCAUGUUGAGCCAUGCUGCUUUCUGGCAUUCCUUUUGGAUUUUCAGUUUACUACCCAACUACCAGUCCUAAUAACAUCAGAUAAAAGGGCUUCCGCUGUGCUGCACUUGUUUUCAAAAACUAUAAAUGCCAUCGACCCAGAGUUAAGUCCAGCCUCAGAGAGACAGAAUAUAAAUACCCAAGUGGCCCUGGGCCACUGAGUUCCUCAGACAUUAUGUGCUAUGGGAGUUCCAGAAAGGGGGAUUGCCUGGUUUUGAGUGCAGAAGGCUUCCUGGAGGAGGCGAGAUUUCUGAUGGGCCUCUGUUAUGAGCUAAAUUGAGUCCACCCCAAAAUUCAGAUGUUCAAAUCCUAACCUGUAGUACCUAAGCAUGUGGCCUUAUUUGGAAGCAGAAGCAUAACAGAGGUAAUUCGUUAAGAUGAGGUCACAGUGGAAGAGGGUGGACCCCAAUCUGAUACAACUCGUGUCCUUAUAAAAAGCAGAAAUUUGAAGACAGACACACAAGAAGAUGAAGGCAGAGACCUGGCUGAUGCGGCUAUAAGCCAAGGAACGCCAAAGAUUGCCAGCAAAGCACCAGCAGCCAGGGAGAGGCCUCGAACAAAUUCUCCCUCCCAGCAAAAAGGAGGAAGGAAGGAACCUCCAAAAGAAGCAGGCCAGGCACAGUGGCUCACGCCUGUAAUCCCAGUACUUUGGGAGGUUAAGGCAGGCGGAUCACCUGAGAUCAAGAGUUCAAGACCAGCCUGGCCAACAUGGUGAAACCUCAUCUCUACAGAAAAAUACAAAAAUUAGUCAGGUGUAGUGGCGUGCACCUGUAGUCCCAGUUACUCGGGAGGCUGAGGCAAGAGAAUCGCUUGAACCUGGGAGGUGGAGGUUGCAGUGAGCCAAGAUCGUGCCAUUGCACUCCAGCCUGGGUGACAGAGCGAGACUCCAUCUCAGAAAAACAAAAAAGAACCCUACUGACACCUGGAUUUCAGACUUCCAGCCUCCAGAACUGUGAGAUGUUACAUUUCUGUCAUUUAAACACCCAGUUUGUAGUACUUUGUUGCAACAGCUCUAGUGAGCUAAUACAGCCUUGUAGGACAGGUAGGAAUUUGUAAUGCACAGAGAAAGCCAACUGGCCACAGUUGUUGAAAAUAAUAGAAUCGAAGCGCCCCUAUCACUACCACCCCAGGCCAUCACUUUCAAAGCUGUUCAAAAUGAUGCAGCCGCGUGAGAAGGCCGGAAGGCCAGGGCGGGAGAUGGGCUCCAGGUGGGCCCAGGCUGCCUGCAGAACCAGCUUGCCUCACUGCCUGGUUGCCAAGGAGCACCUGUGGCUAGGAGGAGAUGCCCAGGAAGAAAAUUUGGCCACAUCCCUGCCUGCCUCCCUGGCAAUGGGUGAUGCUCUCUGCCAGCUGGCCCAGCUCCCCCACCACAUACCUGGCUAGGAGUCAGUAGGAAAACAGUGUGUGUUUGUAGGGCUCUGCACUGAAGGGCAUUAGAUCCAUGCAAAGGCUAAUAAAUUAGAGAUAAGUGGGAUUUGUAGAUUUGCUGGAGGUUAGAGCUGCAGGGUCUGGCAUCAGCUCUGGGUCUUUUCCAUGGCCCCAGGCUGGCUCAGGUGUGAGCUGAAGAGGCAAAACUGUCUGUUUAGGUUGCAUUGGGUUCCCCUGAAAGAUCUGUUGAAGUCCUAACCUCGGGUACCUCUGUUUGUGCUAUUUGCAAACAGGCUCUUUGCAGAUGUAAUCAAGGAAAGAUGAGGCAACGCUGAUUUAGUCAGGCCUUAAUCCAGUGACUGGUGUCUUCAUAAGACAAGGAAAUCUGGACACAGACACACAAAGAGGAAAAAGCCAAAGACACAGAGACACAUGUACACAGGGAGAACUCCAUGGGACAACGCAGGCACAGAUCGGAGUGACGCGGCUGCAAGCCAAGGAGCGCCAAGAUUGCCAGCAACCCCCUGGGGCUGCAAGAGGUGAGAAGGAGCCUUCGGAGGGAACAUGCACUGCUGAUUCCUUGAUUCCAGAUUUCUGACCUCCAGAAGCAUGGGAGAACAGAUUUCCCUUGUUUGAAGGCACCCAGUCUGUGGUCCUUCAUCAUGGCAGCCCUCAGGAAUGGAUACAGGCCCUUCCCUGCCUGCCUGGUGGAGCAGCCUCCAAGGGGAGCCUUUGCUAGCAGGAAGAGGCAUCGCAUGGAGCUCAGACCCGCCUCAGAGGAACUUCUCUCAGCCUCCUCUCUCCGCACACCCGACCAAGGUGUGAAAUCCCUCCCCUUUACCUCUGCCACUUGCAGGUGGCAGGAUGCUGGAGCUGUCCCUGCCUCUUUGUAAAGUGAGGGAAGGGCAGCCCUCUCUGCUCUUUUUUUUUUUUUUUUUGAGACAGAGUCUCACUCUGUCUCCCAGGCUGGAGUGCAAUAGCACGAUCUCGGCUCACUGCAACCUCCGCCUCCCAGGUUCAAGCGAUUCUCCUGCCUCAACCUCCUGAGUAGCUGGAAUUACAGGUGCCUGCCACCACGCCCAGCUAAUUUUGUAUUGUUAGUAGAGCCAGGGUUUCACCAUGUCGGCCAGGCUAGUCUCAAACUCCUGACCUCAGGUGAUCCACCUGCCUCGGCCUCCCAAAGUGCUGCGAUUACAGACAUGAGCCACCACGCCCGGCCUGCUCCACUUCUAAGGCUUCUUGUGACAAUGUAAGAGAAAGGAGAUGACAGAGCUUUGCAACGGGAGGAGGGCUAUGUGUUCUGGUGACCAAUUCACUGUCUUGUGUCGGGACAGGAAGAAGCCCUUCAUACGGGCAGCAGGCUGGGAGCCAGGGAGGAGGAAAGAUCACGAUCCACUCCCUGGUACAUGGCCCUUCUGCACCCCGCAGUCUCCUUCCAGGUGCCACAACGAGAAGGCACACAUCCUUGGCACAGCACUUGAGGCUUUUCACCACUGGCUGCACUCACCCCUCCAGACUCACUGCCUUGCACCAACCCUUUUCCGCCCACCCCACUCUAUGCUGUCCACAGCCUCCACCCCAGCCACCUGAUUCUGCAGGCCAAUGUCACAUUCUUCCAGUCCAGGUUCUAUUCUGGCAUUUCUUGUCAUUAUUUUGCUGAGAAUGUGUCUCUCUUGACUUUGAACUUAUUGAGAGCAGGAAUCAUGACUCAGCCAUAUAUCCCAGCACUUGGCCCAGGGCCUGUCGUUUCCAGGGUAGGUGGUCUAGGCUGAUUGAAGGAAUGGCAUUUAGUCUUUAAAAUGAAAGCAUGUUGCCUAGCUUGGUUAUUUUUGAACUCUAUAAUCAAGGACUACGUUUACCUGAAUAGCCUCUGCAGAACACCAAUUCCGUAAGGUGCUUCACACACACACACCAAUUCUAUCAUUUAAUACAUUUUGGAAAGGCUACAUACUACUACAGCCUCUUUUACAGAUUAGCAAUGUCCAUGAGCGCACUAAAGGUUGAGACAUUCUGCAGUGAAGAAGCCUAUUUCAUUUUGUUUAACCAAGUAUUUCUCAAAUUUAUUUGAUCAUAUGUGGCAGAAAAUGCUGUGUCUGGCAUUCUUCAUUUCCCUCUUCCUCCUUUAACAUGGAACCCCUGAUGUCUUUAGCUUGGCACAUCGCCACCCAGAAUAAAAACUACCUUUCCCAGCUCUUCCUGCAGCUAGGGGCAGCCCUGGGAUAAAUUCUGGACAAUGAAAUACAGGCAGAAGUAAAUCAUAUACGAUUUCCAUGAAGGGACCUUAAACAGAAGUGUGCCCUUCUCUUCCCCACACAUUCCUCCUCCUGUCUGAAAUGUAGAUGCAACUGCUGGCAUUUGAGCAGCCAUCUUGGGCCAUGUGGUAGCUUCUUAUGGAUGAUCUAGGACUAAUUCAAGGGUCUAGAUUUACCUCCAAACUUUGUUUAUCUACAAAAAAUAAAACUCUAUCUUCUUAAAGCUA

Taxonomic tree

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Publications