SNORA43: SNORA43 is a small nucleolar RNA (snoRNA) that is overexpressed in lung cancer stem cells and is inversely associated with survival in non-small cell lung cancer (NSCLC) patients [1]. A SYBR green approach was used to measure the relative mRNA levels of various snoRNAs, including SNORA43, in lung cancer cells [2]. SNORA43, along with SNORA17, is hosted in the introns of the small nucleolar RNA host gene 7 (SNHG7) [3]. SNHG7 is a 3'UTR/bidirectional long non-coding RNA (lncRNA) that encodes smaller snoRNAs, including SNORA43 and SNORA17 [4]. In some tumour genomes, amplification of SNORA43 was observed [5]. Losses of the 3p21.1 region where SNORA26 is located and the 3p25.3 region where SNORA43 is located were also observed [5]. In a study evaluating clinical significance in NSCLC tissues, SNORA3 and SNORA43 were found to have high expression levels in tumour-initiating cells compared to non-tumour-initiating cells [6]. References: 1. PMC6629867 2. PMC7760958 3. PMC7244715 4. PMC3747266 5. PMC5423597 6. PMC4029979