cfa-mir-502: Cfa-mir-502 is a microRNA that has been discovered to be overexpressed in canine mammary tumors (CMT) and is considered a diagnostic target for CMT [PMC9917093]. The role of cfa-mir-502 in CMT needs further exploration [PMC9917093]. Studies have shown that cfa-mir-502 is significantly upregulated in CMT compared to normal tissue [PMC9917093]. In a study comparing Sertoli cell tumors and normal testis, cfa-mir-502 was one of the top five microRNAs with a fold change cut-off of >2, indicating its potential role in Sertoli cell tumors [PMC10135127]. Among these top five microRNAs, cfa-miR-27b, cfa-miR-20a, and cfa-miR-93 were highly expressed in Sertoli cell tumors, while cfa-mir-502 and cfa-miR-500 were less expressed [PMC10135127]. Furthermore, the conservation of miR-502 has been observed across multiple animal species including cow (Bos taurus), dog (Canis lupus familiaris), horse (Equus caballus), gorilla (Gorilla gorilla), rhesus monkey (Macaca mulatta), rabbit (Oryctolagus cuniculus), and Bornean orangutan (Pongo pygmaeus) [PMC10144852]. These findings suggest the potential importance of miR-502 across different species.