SNORA27: SNORA27 is a small nucleolar RNA (snoRNA) that has been studied in various contexts. It is one of the snoRNAs that are part of a signature, which includes SNORA12, SNORA22, SNORA27, SNORA56, SNORA64, SNORA69, SNORA70, SNORA74A, SNORA80, SNORA84, SNORD1A, SNORD1B, SNORD8, SNOR18, SNORD30,SNORD32A ,SNORD34 ,SNORD105B ,SNORD110 and SCARNA8 [PMC8629011]. In the context of STS (soft tissue sarcoma), the expression of ACA39 and two snoRNAs (SNORA11C and 27) increased while the U13 paralog on chromosome 1 showed decreased expression [PMC4491207]. In another study on ageing and osteoarthritis (OA), several snoRNAs including ACA39 and two others (SNOR36 and 27) were found to target helix 68 modifications [PMC7326970]. Additionally in exosomes derived from A33-Exos cells and Ep-CAM-Exos cells several snoRNAs were found to be overexpressed or enriched including snoRNA18,snoRNA27,snoRNA57,snoRNA62,snoRNA68,snoRNA70,snoRNA77,SNOR23,SNOU13 in A33-Exos cells while snoRNA14B,snoR31,SNO77,U3,SNOU13 were enriched in Ep-CAM-Exos cells [PMC7461500]. In proliferating normal B-cells and proliferating CLL cells eight snoRNAs including SNO12,SNO22,SNO27,SNO56,SNO70 ,SND8 ,SND105B,and SCA8 were upregulated and two snoRNAs (SNO80 and SND1A) were downregulated, suggesting their potential role in proliferation [PMC9219770]. Finally, in a study where DEGs (differentially expressed genes) were identified, SNORA27 was one of the four DEGs of unclear function and/or showed borderline differences in gene expression [PMC6428308].