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HAO2-IT1: HAO2-IT1 is a less studied long non-coding RNA (lncRNA) that requires further investigation to understand its functions in hepatocellular carcinoma (HCC) and other tumors [PMC8321115]. In a study, HAO2-IT1 was found to be one of the differentially expressed lncRNAs (DElncRNAs) that showed statistical significance in predicting overall survival (OS) [PMC8321115]. However, there is a lack of literature on HAO2-IT1 in tumorigenesis [PMC9680297]. HAO2-IT1 was found to interact with MT-RNR2 [PMC9680297]. In another study, the subcellular localization of various lncRNAs was determined, and it was found that HAO2-IT1 is located in the cytoplasm [PMC9680297]. Additionally, this study showed that HAO2-IT1 was downregulated in osteosarcoma (OS) samples compared to normal bone tissues [PMC9680297]. Another study also confirmed the downregulation of HAO2-IT1 in OS samples compared to normal bone tissues [PMC9680297].
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