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hsa-mir-658: Hsa-mir-658 is a microRNA that has been reported to be part of the colorectal microRNAome but has not yet been demonstrated as part of the melanoma microRNAome [PMC4516543]. In a study comparing different types of mesenchymal stem cells (MSCs), it was found that hsa-mir-658 was significantly downregulated in melanoma-derived MSCs compared to amniotic fluid-derived MSCs [PMC9319258]. Another study found that hsa-mir-658 showed lower abundance in clinical samples of a certain disease compared to controls [PMC7125074]. BC069792, a specific gene, was found to bind to hsa-mir-658 and act as a molecular sponge, up-regulating the protein expression of the target gene KCNQ4 and inhibiting breast cancer [PMC9976483]. Hsa-mir-658 was also found to be upregulated in 11 diseases [PMC4268797]. It has been suggested that non-hematopoietically derived miRNAs, including hsa-mir-658, can enter and persist in circulation [PMC3117799]. In another study, hsa-mir-658 was identified as one of the top differentially expressed miRNAs associated with a certain condition [PMC7487708]. Hsa-mir-658 was also one of the three miRNAs identified as potential targets for circ_0001789 [PMC9901162]. Finally, in a prognostic prediction model for a specific disease, hsa-mir-658 was one of six miRNAs selected as an accurate predictor [PMC9241030].
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