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Canis lupus familiaris (dog) cfa-miR-1839 URS00005916FD_9615

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cfa-mir-1839: Cfa-mir-1839, a microRNA, was found to be downregulated at 24 hours post-infection (hpi) [PMC7689213]. TRIM71, a predicted target gene of cfa-mir-1839, is known to regulate juvenile-to-adult transition events in nematodes and mammals [PMC7689213]. At 24 hpi, cfa-mir-1839 was one of the 16 differentially expressed miRNAs in infected livers [PMC7689213]. In the study, several miRNAs including cfa-mir-1839 were predicted to regulate IgSF genes [PMC7689213]. The downregulation of hepatic cfa-mir-1839 was hypothesized to possibly play a role in the juvenile-to-adult development of T. canis larvae in puppies' livers [PMC7689213]. However, further investigation is needed to determine if cfa-mir-1839 indeed regulates the juvenile-to-adult transition of T. canis larvae [PMC7689213]. Functional enrichment analysis suggested that cfa-mir-1839 could be associated with the juvenile-to-adult transition of T. canis larvae [PMC7689213]. The structure of a human putative miRNA (hsa-mir-putative-1) was shown to be homologous to cfa-mir-1839 [PMC2767369]. Additionally, sequencing data revealed that cfa-mir-1839 had high read counts in human embryonic stem cells and embryoid bodies [PMC2767369].

Genome locations

Gene Ontology annotations

Sequence

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AAGGUAGAUAGAACAGGUCUUG

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This sequence is found in 7 other species

  1. Capra hircus (goat) miR-1839
  2. Cervus elaphus (red deer) cel-miR-1839
  3. Equus caballus (horse) eca-miR-1839
  4. Macaca fascicularis microRNA miR-1839-5p
  5. Mus musculus (house mouse) mmu-miR-1839-5p
  6. Rattus norvegicus rno-miR-1839-5p
  7. Sus scrofa (pig) ssc-miR-1839-5p
Publications