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bta-mir-148b: Bta-mir-148b is a microRNA that has been found to be differentially expressed in various contexts. In a study comparing different cattle breeds, bta-mir-148b was identified as one of the miRNAs that showed differential expression between the Abondance and Normande breeds, as well as between the Charolais and Normande breeds [PMC7106649]. Another study found that bta-mir-148b was more abundant in extracellular vesicles (EVs) from the oviduct compared to those from the uterus, suggesting its potential role in favoring the implantation process [PMC9594899]. In human tumor cells, bta-mir-148b has been reported to be related to the suppression of proliferation, migration, and invasion [PMC9594899]. Furthermore, bta-mir-148b has been implicated in various biological processes and pathways. It has been found to target genes involved in antigen processing and presentation as well as allograft rejection pathways [PMC5617439]. In cows with metritis (uterine inflammation), bta-mir-148b was downregulated compared to healthy cows [PMC7832875]. Additionally, bta-mir-148b has been shown to potentially target the 3'UTR of bovine MHC-I heavy chain mRNA [PMC5801426]. Overall, these studies highlight the diverse roles and potential regulatory functions of bta-mir-148b in different biological contexts.
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