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Homo sapiens (human) small nucleolar RNA, C/D box 30 (SNORD30) secondary structure diagram

Homo sapiens (human) small nucleolar RNA, C/D box 30 (SNORD30) URS00004E0FA9_9606

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SNORD30: SNORD30 is a C/D box small nucleolar RNA (snoRNA) that has been implicated in various biological processes and diseases. It is part of a signature that includes other snoRNAs such as SNORA12, SNORA22, SNORA27, SNORA56, and SNORA64 [PMC8629011]. In the context of smoldering multiple myeloma (SMM), SNORD30 has been identified as one of the snoRNAs significantly correlated with shorter time to progression [PMC8750018]. It has also been associated with the progression from smoldering to symptomatic multiple myeloma [PMC3766210]. SNORD30 is located within the inside-out gene SNHG1 and is one of eight C/D box snoRNAs hosted by this gene [PMC4378963]. The expression of SNORD30 has been correlated with tumor progression in several studies, making it a potential marker for immune cancers [PMC9149858]. In addition to its role in cancer, SNORD30 has also been implicated in other diseases such as pediatric gliomas and influenza A virus infection [PMC5560661] [PMC9696202]. Furthermore, studies have identified interactions between SNORD30 and specific sites in rRNA molecules, suggesting its involvement in RNA modification processes [PMC5389715] [PMC7668251]. Overall, these findings highlight the diverse roles and potential clinical relevance of SNORD30.

Genome locations

Gene Ontology annotations

Sequence

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GUUUGUGAUGACUUACAUGGAAUCUCGUUCGGCUGAUGACUUGCUGUUGAGACUCUGAAAUCUGAUUUUC

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2D structure Publications