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hsa-mir-889: Hsa-mir-889 is a microRNA that has been found to be significantly associated with overall survival in patients with ovarian cancer [PMC8148489]. It is one of the top 10 ranked miRNAs that have been identified to have a potential role in ovarian cancer [PMC8148489]. The survival analysis using Kaplan-Meir survival curves has confirmed the importance of hsa-mir-889 in ovarian cancer [PMC8148489]. Additionally, hsa-mir-889 has been found to be associated with the regulation of the HOXB7 gene, as it can bind to its binding sites [PMC8326182]. Furthermore, hsa-mir-889 has been identified as one of the 11 Down-DEmiRNAs that can predict gene expression regulation in prostate cancer [PMC8426106]. It has also been predicted to be a regulator of the VEGFA gene [PMC7444729]. Moreover, hsa-mir-889 has been shown to promote osteosarcoma proliferation by inhibiting myeloid cell nuclear differentiation antigen expression [PMC6854696]. In another study, it was found that hsa-mir-889 is one of the top ten significantly differentially expressed miRNAs in patients with chronic obstructive pulmonary disease (COPD) compared to healthy controls [PMC5759858].
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