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ssc-mir-503: ssc-mir-503 is a microRNA that has been found to be up-regulated in various studies [PMC6598998] [PMC7143271] [PMC9651005] [PMC8367414] [PMC6722729]. It has been shown to directly target the EGF gene CDS region and is potentially involved in blood vessel development in the endometrium [PMC7143271]. Additionally, ssc-mir-503 has been found to potentially bind EGF mRNA and is down-regulated in adipocyte differentiation and fatty acid metabolism in pigs [PMC9454643]. It has also been identified as a member of the miR-503 cluster, along with ssc-miR-424-5p, ssc-miR-450a, ssc-miR-450b-5p, ssc-miR450c-5p, and ssc-miR-542-3p, which are commonly affected by ZEN exposure in piglets [PMC9142966]. Furthermore, miRNA-to-mRNA interaction analyses have predicted that ssc-mir-503 may have a putative binding site in the PDK4 3'-UTR region and is up-regulated in the skeletal muscle of AL-T2 gilts [PMC6966835]. Overall, these studies highlight the potential role of ssc-mir-503 in various biological processes and its association with different target genes.
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Gene Ontology annotations
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Sequence
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