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Homo sapiens (human) hsa-miR-151b URS00003E6479_9606

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hsa-mir-151b: Hsa-mir-151b is an upregulated microRNA (miRNA) observed in various biological contexts, including early pregnancy and disease states [PMC8875566]. It is one of the miRNAs used in a classification model to predict the risk of developing gestational diabetes mellitus (GDM) with a high classification efficiency [PMC8377872]. Despite its association with pregnancy, hsa-mir-151b is also expressed in small extracellular vesicles (sEVs) from non-pregnant women, indicating it is not exclusive to pregnancy [PMC8377872]. This miRNA has been identified in both pre- and posttherapeutic lymphoma patients, suggesting a potential role in cancer biology [PMC7880712]. However, there is no direct evidence in the provided context that hsa-mir-151b is implicated as a potential blood biomarker for Alzheimer's disease (AD) [PMC7565463]. It also appears to be involved in competitive binding interactions as part of ceRNA regulatory mechanisms affecting mRNA expression levels [PMC9353269]. Furthermore, hsa-mir-151b's expression has been quantified using RNA sequencing techniques for potential use as a biomarker [PMC8794677], and it has been identified as part of diagnostic classifiers for various sarcomas with high discriminatory power [PMC6959019]. Lastly, its differential expression has been confirmed in GDM cases and its sequence homology suggests functional similarities across species including humans and mice [PMC6493311; PMC8614260].

Genome locations

Gene Ontology annotations

Sequence

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UCGAGGAGCUCACAGUCU

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This sequence is found in 2 other species

  1. Macaca fascicularis microRNA miR-151b-3p
  2. Mus musculus Mus_musculus piRNA piR-mmu-8228675
Relationships

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Publications