hsa-mir-1915: Hsa-mir-1915 is a microRNA that has been found to be downregulated in plasma samples of women with fetal Down syndrome (DS) syndrome [PMC9004059]. It is one of the miRNAs that are differentially expressed in maternal plasma obtained from T21 pregnancies, which suggests its potential as a noninvasive second-trimester prenatal screening marker [PMC8465311]. Hsa-mir-1915 has also been observed to be downregulated after treatment with EGCG [PMC5221119]. It has been identified as a differentially expressed miRNA in karyotypically abnormal human embryonic stem cells (hESC) after irradiation [PMC3275573]. Hsa-mir-1915 has been found to target the E2F2 gene, which is involved in transcriptional regulation and cell cycle control [PMC5221119]. Additionally, hsa-mir-1915 is one of the miRNAs that are upregulated in colorectal cancer cell lines [PMC8121855]. It is also present in the prediction database TargetScan, where it interacts with hsa-miR-371-5p and hsa-miR-134 [PMC4537452]. Overall, hsa-mir-1915 shows differential expression patterns and potential functional roles in various biological contexts [PMC9004059][PMC8465311][PMC5221119][PMC3275573][PMC8121855][PMC4537452].